Bio-structural monitoring of bone mineral alterations through electromechanical impedance measurements of a Piezo-device joined to a tooth.
Bio-monitoring
Bone mass reduction
Bone mineral alterations
Bone mineral density
Electromechanical impedance technique
Micro-CT
Piezo-device
Spectroscopy
Structural health monitoring
Journal
Biomedical engineering letters
ISSN: 2093-985X
Titre abrégé: Biomed Eng Lett
Pays: Germany
ID NLM: 101567784
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
22
05
2020
revised:
03
08
2020
accepted:
09
09
2020
entrez:
16
11
2020
pubmed:
17
11
2020
medline:
17
11
2020
Statut:
epublish
Résumé
Bone presents different systemic functionalities as calcium phosphate reservoir, organ protection, among others. For that reason, the bone health conditions are essential to keep in equilibrium the metabolism of several body systems. Different technologies exist to diagnose bone conditions with invasive methods based on ionizing radiation. Therefore, there is a challenge to develop new ways to evaluate bone alterations in a noninvasive form. This study shows the assessment of a piezo-actuated device acting on a human tooth for the bio-monitoring of bone alterations. The bone diagnosis is performed by applying the electromechanical impedance technique (EMI), commonly used in structural health monitoring. For the experimental tests, five bone samples were prepared, and one was chosen as the monitoring. All samples were put in a decalcifying substance (TBD1 acid-base) at different times to emulate localized bone mineral alterations. Bone reductions were computed by using X-ray micro-computed tomography analyzing the morphometry. Electrical resistance measurements (piezo-device) were taken for the monitoring specimen meanwhile it was partially decalcified during 8520 seconds. In the frequency spectrum, several observation windows showed that the bone alterations gradually changed the electrical resistance signals which were quantified statistically. Results evidenced that the bone density changes are correlated with the electrical resistance measurements; these changes presented an exponential behavior as much as in the calculated index, and bone mineral reduction. The results demonstrated that bone alterations exhibit linear dependence with the computed statistical indexes. This result confirms that it is possible to observe the bone changes from the teeth as a future application.
Identifiants
pubmed: 33194251
doi: 10.1007/s13534-020-00170-9
pii: 170
pmc: PMC7655898
doi:
Types de publication
Journal Article
Langues
eng
Pagination
603-617Commentaires et corrections
Type : ErratumIn
Informations de copyright
© Korean Society of Medical and Biological Engineering 2020, corrected publication 2020.
Déclaration de conflit d'intérêts
Conflicts of interestThe authors declare that they do not have conflicts of interest.
Références
Med Oral Patol Oral Cir Bucal. 2011 Nov 01;16(7):e905-13
pubmed: 21743400
Biomed Eng Lett. 2019 Aug 10;9(4):435-447
pubmed: 31799013
Ann Biomed Eng. 2017 Apr;45(4):1122-1132
pubmed: 27830489
J Oral Rehabil. 2001 May;28(5):425-32
pubmed: 11380782
Angle Orthod. 2015 May;85(3):454-60
pubmed: 25181252
Am J Orthod Dentofacial Orthop. 2001 May;119(5):498-504
pubmed: 11343021
Dental Press J Orthod. 2013 Sep-Oct;18(5):78-83
pubmed: 24352392
J Bone Miner Res. 2010 Jul;25(7):1468-86
pubmed: 20533309
Philos Trans A Math Phys Eng Sci. 2007 Feb 15;365(1851):373-92
pubmed: 17255044
Osteoarthritis Cartilage. 2011 Nov;19(11):1343-8
pubmed: 21884807
Med Eng Phys. 2016 Aug;38(8):701-7
pubmed: 27185035
Sensors (Basel). 2018 Apr 24;18(5):
pubmed: 29695067
Calcif Tissue Int. 2005 Nov;77(5):275-80
pubmed: 16307388
Sensors (Basel). 2017 Oct 27;17(11):
pubmed: 29077009
Sensors (Basel). 2019 Jan 07;19(1):
pubmed: 30621038
J Bone Miner Res. 1995 Feb;10(2):175-7
pubmed: 7754796
J Biomech. 2015 Jul 16;48(10):1713-20
pubmed: 26070645
Int J Obes Relat Metab Disord. 1999 Oct;23(10):1079-84
pubmed: 10557029
Osteoporos Int. 2000;11(8):669-74
pubmed: 11095169
Am J Forensic Med Pathol. 2004 Dec;25(4):276-84
pubmed: 15577515
Int J Oral Maxillofac Implants. 2015 Mar-Apr;30(2):286-92
pubmed: 25830388
BMJ. 1992 Nov 7;305(6862):1124-8
pubmed: 1463947
J Pineal Res. 2010 Nov;49(4):356-63
pubmed: 20666975
Eur J Clin Nutr. 2004 Nov;58(11):1479-84
pubmed: 15138459
J Oral Biol Craniofac Res. 2013 May-Aug;3(2):92-7
pubmed: 25737892
Sensors (Basel). 2017 Jan 27;17(2):
pubmed: 28134811
Bone. 2001 Dec;29(6):517-22
pubmed: 11728921
Arch Osteoporos. 2013;8:136
pubmed: 24113837
Int J Numer Method Biomed Eng. 2019 Feb;35(2):e3160
pubmed: 30281937