TET-mediated 5-methylcytosine oxidation in tRNA promotes translation.

5-Methylcytosine / chemistry Animals DNA-Binding Proteins / chemistry Dioxygenases Embryonic Stem Cells / metabolism Mice Mice, Knockout Protein Biosynthesis Proto-Oncogene Proteins / chemistry RNA, Transfer / chemistry
5-methylcytocine RNA modification demethylation transfer RNA translational regulation

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
Historique:
received: 06 05 2020
revised: 29 10 2020
accepted: 16 11 2020
pubmed: 18 11 2020
medline: 25 8 2021
entrez: 17 11 2020
Statut: ppublish

Résumé

Oxidation of 5-methylcytosine (5mC) in DNA by the ten-eleven translocation (TET) family of enzymes is indispensable for gene regulation in mammals. More recently, evidence has emerged to support a biological function for TET-mediated m

Identifiants

DOI: 10.1074/jbc.RA120.014226 PMID: 33199375 PMC: PMC7949041
pubmed: 33199375
pii: S0021-9258(20)00075-7
doi: 10.1074/jbc.RA120.014226
pmc: PMC7949041
pii:
doi:

Substances chimiques

DNA-Binding Proteins 0
Proto-Oncogene Proteins 0
5-Methylcytosine 6R795CQT4H
RNA, Transfer 9014-25-9
Dioxygenases EC 1.13.11.-
Tet2 protein, mouse EC 1.13.11.-

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

100087

Subventions

Organisme : NIGMS NIH HHS
ID : F31 GM139325
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM118501
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM133721
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM132039
Pays : United States

Informations de copyright

Copyright © 2021. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Conflict of interest The authors declare that they have no conflicts of interest with the contents of this article.

Références

Nat Cell Biol. 2019 Aug;21(8):978-990
pubmed: 31358969
Nat Struct Mol Biol. 2012 Sep;19(9):900-5
pubmed: 22885326
Science. 2011 Sep 2;333(6047):1303-7
pubmed: 21817016
Wiley Interdiscip Rev RNA. 2019 Jan;10(1):e1510
pubmed: 30311405
Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2561-2570
pubmed: 30692263
Science. 2016 Jan 15;351(6270):282-5
pubmed: 26816380
Nat Commun. 2012 Jul 03;3:937
pubmed: 22760636
Genes Dev. 2010 Aug 1;24(15):1590-5
pubmed: 20679393
Cell. 2013 Dec 19;155(7):1545-55
pubmed: 24315485
Cell Discov. 2015 Jun 09;1:15010
pubmed: 27462411
Nat Chem Biol. 2016 Jul;12(7):546-51
pubmed: 27214402
Nature. 2018 Feb 1;554(7690):123-127
pubmed: 29364877
Mol Cell. 2019 Sep 19;75(6):1188-1202.e11
pubmed: 31399345
Biochemistry. 2019 Feb 5;58(5):411-421
pubmed: 30387995
Trends Biochem Sci. 2013 Oct;38(10):480-4
pubmed: 23932479
EMBO J. 2014 Sep 17;33(18):2020-39
pubmed: 25063673
Biomolecules. 2017 Mar 16;7(1):
pubmed: 28300792
J Am Chem Soc. 2017 Feb 8;139(5):1766-1769
pubmed: 28107630
RNA. 2015 Sep;21(9):1532-43
pubmed: 26160102
Methods Enzymol. 2016;573:365-85
pubmed: 27372762
EMBO J. 2016 Oct 4;35(19):2104-2119
pubmed: 27497299
Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11290-5
pubmed: 16040803
EMBO J. 2015 Sep 14;34(18):2350-62
pubmed: 26271101
Nucleic Acids Res. 2017 Jul 7;45(12):7401-7415
pubmed: 28472312
Nat Commun. 2016 Jun 30;7:12039
pubmed: 27356879
J Biol Chem. 2016 Nov 11;291(46):24293-24303
pubmed: 27703015
Nucleic Acids Res. 2018 Jan 4;46(D1):D303-D307
pubmed: 29106616
Proc Natl Acad Sci U S A. 2007 May 22;104(21):8845-50
pubmed: 17502605
PLoS One. 2012;7(9):e45031
pubmed: 23028748
Cold Spring Harb Perspect Biol. 2014 May 01;6(5):a019133
pubmed: 24789823
Science. 2009 May 15;324(5929):930-5
pubmed: 19372391
Cell. 2016 Oct 20;167(3):816-828.e16
pubmed: 27745969
J Biol Chem. 2014 Feb 28;289(9):5986-96
pubmed: 24394411
Nucleic Acids Res. 2009 Apr;37(5):1616-27
pubmed: 19151083
Cell Mol Life Sci. 2018 Apr;75(8):1483-1497
pubmed: 29103146
Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12799-804
pubmed: 21768390
Cell. 2015 Jun 18;161(7):1606-18
pubmed: 26052047
Science. 2005 Jul 1;309(5731):140-2
pubmed: 15905365
Mol Cell Biol. 2013 Apr;33(8):1561-70
pubmed: 23401851
Am J Hum Genet. 2012 May 4;90(5):847-55
pubmed: 22541559
Biochemistry. 2010 Jun 22;49(24):4934-44
pubmed: 20459084
Epigenomics. 2010 Oct;2(5):709-15
pubmed: 22122054
Mol Cell. 2014 Oct 23;56(2):286-297
pubmed: 25263596
Nat Rev Genet. 2013 Mar;14(3):204-20
pubmed: 23400093
Nat Rev Genet. 2012 May 29;13(7):484-92
pubmed: 22641018
Mol Cell. 2016 Oct 20;64(2):416-430
pubmed: 27768875
Science. 2011 Sep 2;333(6047):1300-3
pubmed: 21778364

Auteurs

Hui Shen (H)

Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Robert Jordan Ontiveros (RJ)

Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Graduate Group in Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Michael C Owens (MC)

Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Graduate Group in Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Monica Yun Liu (MY)

Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Uday Ghanty (U)

Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Rahul M Kohli (RM)

Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Kathy Fange Liu (KF)

Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: liufg@penmeddcine.upenn.edu.

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrimidines › Pyrimidinones › Cytosine › 5-Méthyl-cytosine › TET-mediated 5-methylcytosine oxidation in...
questionsmedicales.fr › Eucaryotes › Animaux › TET-mediated 5-methylcytosine oxidation in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de liaison à l'ADN › TET-mediated 5-methylcytosine oxidation in...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxygénases › Dioxygenases › TET-mediated 5-methylcytosine oxidation in...
questionsmedicales.fr › Cellules › Cellules souches › Cellules souches pluripotentes › Cellules souches embryonnaires › TET-mediated 5-methylcytosine oxidation in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › TET-mediated 5-methylcytosine oxidation in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › TET-mediated 5-methylcytosine oxidation in...
questionsmedicales.fr › Phénomènes génétiques › Expression des gènes › Biosynthèse des protéines › TET-mediated 5-methylcytosine oxidation in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines tumorales › Protéines oncogènes › Protéines proto-oncogènes › TET-mediated 5-methylcytosine oxidation in...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN de transfert › TET-mediated 5-methylcytosine oxidation in...