Endovascular management of torcular dural sinus malformations in children: the role of straight sinus occlusion.


Journal

Journal of neurointerventional surgery
ISSN: 1759-8486
Titre abrégé: J Neurointerv Surg
Pays: England
ID NLM: 101517079

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 21 09 2020
revised: 26 10 2020
accepted: 27 10 2020
pubmed: 18 11 2020
medline: 27 4 2021
entrez: 17 11 2020
Statut: ppublish

Résumé

Torcular dural sinus malformations (tDSMs) with arteriovenous shunts are rare congenital intracranial vascular malformations that carry a high rate of neurologic impairment and death in the neonatal, infant and young pediatric population. Their impact on brain venous drainage, especially the deep venous system, is one of the key factors in the clinical prognosis and natural history of the disease. We describe our therapeutic strategy for tDSMs, disconnecting the reflux into the deep venous system by performing an endovascular straight sinus occlusion. Among all children with dural sinus malformations seen between 2002 and 2020, we retrospectively reviewed those with tDSM in whom straight sinus occlusion had been performed. Our databank included nine patients with tDSM that were embolized. Mean age at the clinical onset was 8.9±9.6 months (min-max=0-31). Five patients presented a significant reflux in the straight sinus on digital subtraction angiography. Those patients were initially clinically worse (mean modified Rankin Scale (mRS) 3.8) than those who did not present with reflux (mean mRS 2.25), this reflux being responsible for intraventricular hemorrhage in three patients. The reflux was suppressed by transarterial embolization in one patient and by transvenous straight sinus occlusion in four patients. Staged endovascular treatment resulted in a complete cure in six patients without complications, and clinical improvement in all patients. Straight sinus occlusion is a feasible technique that needs to be considered in the treatment strategy for tDSM with deep venous reflux in order to avoid or minimize brain damage.

Sections du résumé

BACKGROUND BACKGROUND
Torcular dural sinus malformations (tDSMs) with arteriovenous shunts are rare congenital intracranial vascular malformations that carry a high rate of neurologic impairment and death in the neonatal, infant and young pediatric population. Their impact on brain venous drainage, especially the deep venous system, is one of the key factors in the clinical prognosis and natural history of the disease. We describe our therapeutic strategy for tDSMs, disconnecting the reflux into the deep venous system by performing an endovascular straight sinus occlusion.
METHODS METHODS
Among all children with dural sinus malformations seen between 2002 and 2020, we retrospectively reviewed those with tDSM in whom straight sinus occlusion had been performed.
RESULTS RESULTS
Our databank included nine patients with tDSM that were embolized. Mean age at the clinical onset was 8.9±9.6 months (min-max=0-31). Five patients presented a significant reflux in the straight sinus on digital subtraction angiography. Those patients were initially clinically worse (mean modified Rankin Scale (mRS) 3.8) than those who did not present with reflux (mean mRS 2.25), this reflux being responsible for intraventricular hemorrhage in three patients. The reflux was suppressed by transarterial embolization in one patient and by transvenous straight sinus occlusion in four patients. Staged endovascular treatment resulted in a complete cure in six patients without complications, and clinical improvement in all patients.
CONCLUSION CONCLUSIONS
Straight sinus occlusion is a feasible technique that needs to be considered in the treatment strategy for tDSM with deep venous reflux in order to avoid or minimize brain damage.

Identifiants

pubmed: 33199540
pii: neurintsurg-2020-016888
doi: 10.1136/neurintsurg-2020-016888
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

278-283

Informations de copyright

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Stanislas Smajda (S)

Interventional Neuroradiology, The Fondation Adolphe de Rothschild Hospital, Paris, France stanis_s@hotmail.com.

Michael Söderman (M)

Neuroradiology, Karolinska Universitetssjukhuset, Stockholm, Sweden.
Karolinska Institutet Department of Clinical Neuroscience, Stockholm, Sweden.

Georg Dorfmüller (G)

Department of Pediatric Neurosurgery, The Fondation Adolphe de Rothschild Hospital, Paris, France.

Nathalie Dorison (N)

Department of Pediatric Neurosurgery, The Fondation Adolphe de Rothschild Hospital, Paris, France.

Marie-Claire Nghe (MC)

Department of Anesthesiology and Intensive Care, The Fondation Adolphe de Rothschild Hospital, Paris, France.

Georges Rodesch (G)

Diagnostic and Interventional Neuroradiology Department, Hôpital Foch, Suresnes, France.

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Classifications MeSH