New insights into the role of imaging in polymyalgia rheumatica.


Journal

Rheumatology (Oxford, England)
ISSN: 1462-0332
Titre abrégé: Rheumatology (Oxford)
Pays: England
ID NLM: 100883501

Informations de publication

Date de publication:
02 03 2021
Historique:
received: 28 07 2020
revised: 05 09 2020
accepted: 09 09 2020
pubmed: 18 11 2020
medline: 29 6 2021
entrez: 17 11 2020
Statut: ppublish

Résumé

PMR is an inflammatory rheumatic disease of elderly people characterized by pain and stiffness in the neck, shoulder and pelvic girdles. No specific diagnostic confirmatory tests exist and clinical symptoms, as well as increased acute phase reactants, are unspecific. The diagnostic value of imaging including ultrasound, MRI and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) with/without CT for PMR is increasingly studied. These techniques, particularly FDG-PET/CT, may help to detect underlying GCA in PMR patients with an incomplete response to glucocorticoids and/or recurrent relapses. Recent imaging studies provide novel insights into the anatomical basis of inflammation in PMR, particularly at hip and spine, which may help to distinguish this disease from other mimicking conditions. In this review, we discuss novel insights into the pathoanatomy of PMR, compare the diagnostic values of different imaging techniques and summarize current data on the role of imaging for monitoring and outcome prediction.

Identifiants

pubmed: 33200216
pii: 5983879
doi: 10.1093/rheumatology/keaa646
doi:

Substances chimiques

Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1016-1033

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Auteurs

Dario Camellino (D)

Division of Rheumatology, "La Colletta" Hospital, Local Health Trust 3, Arenzano, Italy.
Autoimmunology Laboratory, University of Genoa, Genoa, Italy.

Christina Duftner (C)

Department of Internal Medicine, Clinical Division of Internal Medicine II, Medical University of Innsbruck/Tirol Kliniken, Innsbruck, Austria.

Christian Dejaco (C)

Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria.
Department of Rheumatology, Hospital of Brunico (SABES-ASDAA), Brunico, Italy.

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Classifications MeSH