ONCOR: design of the Dutch cardio-oncology registry.
Cardio-oncology
Registries
Research design
Journal
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
ISSN: 1568-5888
Titre abrégé: Neth Heart J
Pays: Netherlands
ID NLM: 101095458
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
accepted:
20
10
2020
pubmed:
18
11
2020
medline:
18
11
2020
entrez:
17
11
2020
Statut:
ppublish
Résumé
The relative new subspecialty 'cardio-oncology' was established to meet the growing demand for an interdisciplinary approach to the management of cancer therapy-related cardiovascular adverse events. In recent years, specialised cardio-oncology services have been implemented worldwide, which all strive to improve the cardiovascular health of cancer patients. However, limited data are currently available on the outcomes and experiences of these specialised services, and optimal strategies for cardio-oncological care have not been established. The ONCOR registry has been created for prospective data collection and evaluation of cardio-oncological care in daily practice. Dutch hospitals using a standardised cardio-oncology care pathway are included in this national, multicentre, observational cohort study. All patients visiting these cardio-oncology services are eligible for study inclusion. Data collection at baseline consists of the (planned) cancer treatment and the cardiovascular risk profile, which are used to estimate the cardiotoxic risk. Information regarding invasive and noninvasive tests is collected during the time patients receive cardio-oncological care. Outcome data consist of the incidence of cardiovascular complications and major adverse cardiac events, and the impact of these events on the oncological treatment. Outcomes of the ONCOR registry may aid in gaining more insight into the incidence of cancer therapy-related cardiovascular complications. The registry facilitates research on mechanisms of cardiovascular complications and on diagnostic, prognostic and therapeutic strategies. In addition, it provides a platform for future (interventional) studies. Centres with cardio-oncology services that are interested in contributing to the ONCOR registry are hereby invited to participate.
Sections du résumé
BACKGROUND
BACKGROUND
The relative new subspecialty 'cardio-oncology' was established to meet the growing demand for an interdisciplinary approach to the management of cancer therapy-related cardiovascular adverse events. In recent years, specialised cardio-oncology services have been implemented worldwide, which all strive to improve the cardiovascular health of cancer patients. However, limited data are currently available on the outcomes and experiences of these specialised services, and optimal strategies for cardio-oncological care have not been established.
AIM
OBJECTIVE
The ONCOR registry has been created for prospective data collection and evaluation of cardio-oncological care in daily practice.
METHODS
METHODS
Dutch hospitals using a standardised cardio-oncology care pathway are included in this national, multicentre, observational cohort study. All patients visiting these cardio-oncology services are eligible for study inclusion. Data collection at baseline consists of the (planned) cancer treatment and the cardiovascular risk profile, which are used to estimate the cardiotoxic risk. Information regarding invasive and noninvasive tests is collected during the time patients receive cardio-oncological care. Outcome data consist of the incidence of cardiovascular complications and major adverse cardiac events, and the impact of these events on the oncological treatment.
DISCUSSION
CONCLUSIONS
Outcomes of the ONCOR registry may aid in gaining more insight into the incidence of cancer therapy-related cardiovascular complications. The registry facilitates research on mechanisms of cardiovascular complications and on diagnostic, prognostic and therapeutic strategies. In addition, it provides a platform for future (interventional) studies. Centres with cardio-oncology services that are interested in contributing to the ONCOR registry are hereby invited to participate.
Identifiants
pubmed: 33201485
doi: 10.1007/s12471-020-01517-8
pii: 10.1007/s12471-020-01517-8
pmc: PMC8062648
doi:
Types de publication
Journal Article
Langues
eng
Pagination
288-294Références
J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
Circulation. 2015 Jun 2;131(22):1981-8
pubmed: 25948538
Eur Heart J. 2019 Dec 21;40(48):3889-3897
pubmed: 31761945
Mayo Clin Proc. 2014 Sep;89(9):1287-306
pubmed: 25192616
Curr Oncol. 2019 Jun;26(3):e322-e327
pubmed: 31285675
Eur J Heart Fail. 2018 Dec;20(12):1721-1731
pubmed: 30191649
Maturitas. 2017 Nov;105:37-45
pubmed: 28583397
Neth Heart J. 2018 Nov;26(11):521-532
pubmed: 30141030
Circulation. 2020 Jan 14;141(2):87-89
pubmed: 31928434
Heart Fail Clin. 2017 Apr;13(2):347-359
pubmed: 28279420
N Engl J Med. 2016 Oct 13;375(15):1457-1467
pubmed: 27732808
Cardiologia. 1996 Sep;41(9):887-91
pubmed: 8983846
Eur Heart J Cardiovasc Imaging. 2014 Oct;15(10):1063-93
pubmed: 25239940
Lancet. 2019 Sep 21;394(10203):1041-1054
pubmed: 31443926
Lancet Oncol. 2007 Sep;8(9):784-96
pubmed: 17714993
Eur Heart J. 2019 Jun 7;40(22):1756-1763
pubmed: 30085070
Ann Oncol. 2020 Feb;31(2):171-190
pubmed: 31959335
Eur Heart J. 2016 Sep 21;37(36):2768-2801
pubmed: 27567406
CA Cancer J Clin. 2019 Sep;69(5):363-385
pubmed: 31184787
Ned Tijdschr Geneeskd. 2015;159:A9269
pubmed: 26577382
Nat Rev Cardiol. 2015 May;12(5):312-6
pubmed: 25781411