Presence of a left common pulmonary vein and pulmonary vein anatomical characteristics as predictors of outcome following cryoballoon ablation for paroxysmal atrial fibrillation.


Journal

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
ISSN: 1572-8595
Titre abrégé: J Interv Card Electrophysiol
Pays: Netherlands
ID NLM: 9708966

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 07 08 2020
accepted: 10 11 2020
pubmed: 19 11 2020
medline: 27 10 2021
entrez: 18 11 2020
Statut: ppublish

Résumé

Pulmonary vein (PV) isolation using cryoballoon ablation (CBA) is a common therapy for patients with drug-refractory paroxysmal atrial fibrillation (PAF). However, initial CBA is successful in only 70-80% of patients. The role of an atypical left common PV (LCPV) and PV anatomical indices on CBA outcomes remains unclear. We followed 80 patients (age 60.7 ± 9.7, 31 % women) with PAF undergoing CBA for 1-year post-procedure for the development of recurrent atrial arrhythmias (AA). Recurrence was assessed by documented AA on EKG or any form of long-term cardiac rhythm monitoring. The presence of an LCPV and individual PV diameters were evaluated using cardiac CT. Based on the maximum and minimum PV ostial diameters, the eccentricity index (EI), ovality index (OI), and PV ostial area (PVA) were calculated for all the veins. A multivariable Cox-proportional hazard model assessed whether the presence of an LCPV or PV anatomic indices (EI, OI, and PVA) predicted recurrence of AA following CBA. After 1-year follow-up, 19 (23.7%) participants developed recurrence of AA. On multivariable regression, the presence of an LCPV did not predict the recurrence of AA (p = 0.38). Among the PV anatomical indices, on univariate analysis, only the area of the left inferior PV showed a trend towards predicting recurrence, though this result was not significant on multivariate analysis (p = 0.09). In patients with PAF, neither the presence of an LCPV nor individual PV anatomical indices predicted recurrence of AA following CBA.

Identifiants

pubmed: 33206281
doi: 10.1007/s10840-020-00916-6
pii: 10.1007/s10840-020-00916-6
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

409-417

Informations de copyright

© 2020. Springer Science+Business Media, LLC, part of Springer Nature.

Références

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Auteurs

Abhishek Bose (A)

Division of Cardiology, Saint Vincent Hospital, Worcester, MA, 01604, USA. Abhishek.Bose@stvincenthospital.com.

Parag A Chevli (PA)

Section of Hospital Medicine, Department of Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Gregory Berberian (G)

Department of Radiology, Saint Vincent Hospital, Worcester, MA, USA.

Jerzy Januszkiewicz (J)

Department of Radiology, Saint Vincent Hospital, Worcester, MA, USA.

Ghasan Ahmad (G)

Department of Radiology, University of Maryland Medical Center, Baltimore, MD, USA.

Zeba Hashmath (Z)

Department of Internal Medicine, Saint Vincent Hospital, Worcester, MA, USA.

Ajay K Mishra (AK)

Department of Internal Medicine, Saint Vincent Hospital, Worcester, MA, USA.

Douglas Laidlaw (D)

Division of Cardiology, Saint Vincent Hospital, Worcester, MA, 01604, USA.

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