Prevalence of Hepatitis B Virus Markers in Patients with Autoimmune Inflammatory Rheumatic Diseases in Italy.
HBV markers
HBV vaccine
immunosuppressive therapy
rheumatic patients
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
16 Nov 2020
16 Nov 2020
Historique:
received:
23
09
2020
revised:
11
11
2020
accepted:
13
11
2020
entrez:
19
11
2020
pubmed:
20
11
2020
medline:
20
11
2020
Statut:
epublish
Résumé
Chronic hepatitis B virus (HBV) infection may be reactivated by immunosuppressive drugs in patients with autoimmune inflammatory rheumatic diseases. This study evaluates HBV serum markers' prevalence in rheumatic outpatients belonging to Spondyloarthritis, Chronic Arthritis and Connective Tissue Disease diagnostic groups in Italy. The study enrolled 302 subjects, sex ratio (M/F) 0.6, mean age ± standard deviation 57 ± 15 years, 167 (55%) of whom were candidates for immunosuppressive therapy. The Spondyloarthritis group included 146 subjects, Chronic Arthritis 75 and Connective Tissue Disease 83 (two patients had two rheumatic diseases; thus, the sum is 304 instead of 302). Ten subjects (3%) reported previous anti-HBV vaccination and tested positive for anti-HBs alone with a titer still protective (>10 IU/mL). Among the remaining 292 subjects, the prevalence of positivity for HBsAg, isolated anti-HBc, anti-HBc/anti-HBs, and any HBV marker was 2%, 4%, 18%, and 24%, respectively. A total of 26/302 (9%) patients with γ-globulin levels ≤0.7 g/dL were more frequently (
Identifiants
pubmed: 33207663
pii: microorganisms8111792
doi: 10.3390/microorganisms8111792
pmc: PMC7696870
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Ann Rheum Dis. 2020 Jan;79(1):39-52
pubmed: 31413005
Int Rev Immunol. 2010 Jun;29(3):247-69
pubmed: 20521925
Best Pract Res Clin Rheumatol. 2015 Apr;29(2):319-42
pubmed: 26362747
Blood Transfus. 2014 Jan;12 Suppl 1:s63-8
pubmed: 23522882
Open Rheumatol J. 2016 Aug 31;10:39-48
pubmed: 27708728
Medicine (Baltimore). 2011 Nov;90(6):359-71
pubmed: 22033451
Hepatology. 1988 Jul-Aug;8(4):766-70
pubmed: 2968945
RMD Open. 2019 Sep 19;5(2):e001041
pubmed: 31673420
Dig Liver Dis. 2007 May;39(5):397-408
pubmed: 17382608
J Hepatol. 2017 Aug;67(2):370-398
pubmed: 28427875
J Hepatol. 2012 Jul;57(1):167-85
pubmed: 22436845
Scand J Infect Dis. 2001;33(8):618-21
pubmed: 11525358
J Prev Med Public Health. 2005 May;38(2):170-4
pubmed: 16315754
Clin Infect Dis. 2008 Sep 1;47(5):e52-6
pubmed: 18643758
Clin Infect Dis. 1998 Apr;26(4):895-7
pubmed: 9564471
Gastroenterology. 1992 Aug;103(2):590-4
pubmed: 1386048
N Engl J Med. 1998 Dec 24;339(26):1905-13
pubmed: 9862947
Pathol Biol (Paris). 2010 Aug;58(4):258-66
pubmed: 20116937
N Engl J Med. 2008 Oct 2;359(14):1486-500
pubmed: 18832247
World J Hepatol. 2014 May 27;6(5):284-92
pubmed: 24868322
Gastroenterology. 2015 Jan;148(1):221-244.e3
pubmed: 25447852
Nat Rev Gastroenterol Hepatol. 2014 Apr;11(4):209-19
pubmed: 24247262
Hepatol Commun. 2020 Jan 20;4(3):329-341
pubmed: 32140652
Hum Vaccin Immunother. 2019;15(5):1177-1182
pubmed: 30676860
Eur J Rheumatol. 2016 Mar;3(1):25-28
pubmed: 27708965
World J Gastroenterol. 2015 Sep 28;21(36):10274-89
pubmed: 26420955
World J Gastroenterol. 2014 Apr 7;20(13):3516-24
pubmed: 24707134
Arthritis Care Res (Hoboken). 2010 May;62(5):704-11
pubmed: 20461789
Middle East J Dig Dis. 2015 Oct;7(4):233-40
pubmed: 26609352
Scand J Infect Dis. 2000;32(3):315-6
pubmed: 10879605
Clin Liver Dis. 2016 Nov;20(4):607-628
pubmed: 27742003
Hepatology. 2009 May;49(5 Suppl):S156-65
pubmed: 19399803
J Infect. 2001 Oct;43(3):187-90
pubmed: 11798257
Lancet. 2014 Dec 6;384(9959):2053-63
pubmed: 24954675
Blood Transfus. 2013 Apr;11(2):281-8
pubmed: 23399361
J Viral Hepat. 2011 Sep;18 Suppl 1:1-16
pubmed: 21824223
J Virol. 2007 Jul;81(14):7351-62
pubmed: 17475655
Viruses. 2019 Sep 14;11(9):
pubmed: 31540124
Lancet. 1984 Jul 21;2(8395):173
pubmed: 6146076
Hepatology. 2009 May;49(5 Suppl):S13-21
pubmed: 19399811
J Infect Dis. 2005 May 1;191(9):1435-41
pubmed: 15809901
JAMA. 1987 Sep 4;258(9):1193-5
pubmed: 2957523
Nat Commun. 2016 Jan 08;7:10369
pubmed: 26742691
Hepatology. 2018 Apr;67(4):1560-1599
pubmed: 29405329
J Clin Med. 2020 Jan 11;9(1):
pubmed: 31940817
Hum Vaccin Immunother. 2016 Jul 2;12(7):1847-51
pubmed: 27065099
J Hepatol. 2015 Nov;63(5):1238-53
pubmed: 26150256
Blood Transfus. 2019 Nov;17(6):409-417
pubmed: 31846606