Impact of the COVID-19 Pandemic on Antimicrobial Consumption and Hospital-Acquired Candidemia and Multidrug-Resistant Bloodstream Infections.

COVID-19 anti-infective agents antimicrobial stewardship bacteremia candidemia

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
17 Nov 2020
Historique:
received: 17 10 2020
revised: 10 11 2020
accepted: 15 11 2020
entrez: 20 11 2020
pubmed: 21 11 2020
medline: 21 11 2020
Statut: epublish

Résumé

During the COVID-19 pandemic, the implementation of antimicrobial stewardship strategies has been recommended. This study aimed to assess the impact of the COVID-19 pandemic in a tertiary care Spanish hospital with an active ongoing antimicrobial stewardship programme (ASP). For a 20-week period, we weekly assessed antimicrobial consumption, incidence density, and crude death rate per 1000 occupied bed days of candidemia and multidrug-resistant (MDR) bacterial bloodstream infections (BSI). We conducted a segmented regression analysis of time series. Antimicrobial consumption increased +3.5% per week (

Identifiants

pubmed: 33212785
pii: antibiotics9110816
doi: 10.3390/antibiotics9110816
pmc: PMC7698104
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Consejería de Salud, Junta de Andalucía
ID : PI-0361-2010

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Auteurs

Ana Belen Guisado-Gil (AB)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.
Clinical Unit of Pharmacy, University Hospital Virgen del Rocio, 41013 Seville, Spain.

Carmen Infante-Domínguez (C)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

Germán Peñalva (G)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

Julia Praena (J)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

Cristina Roca (C)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

María Dolores Navarro-Amuedo (MD)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

Manuela Aguilar-Guisado (M)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

Nuria Espinosa-Aguilera (N)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

Manuel Poyato-Borrego (M)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.
Clinical Unit of Emergency, University Hospital Virgen del Rocio, 41013 Seville, Spain.

Nieves Romero-Rodríguez (N)

Clinical Unit of Cardiology, University Hospital Virgen del Rocio, 41013 Seville, Spain.
Department of Medicine, University of Seville, 41004 Seville, Spain.

Teresa Aldabó (T)

Intensive Care Department, University Hospital Virgen del Rocio, 41013 Seville, Spain.

Sonsoles Salto-Alejandre (S)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

Maite Ruiz-Pérez de Pipaón (M)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

José Antonio Lepe (JA)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

Guillermo Martín-Gutiérrez (G)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

María Victoria Gil-Navarro (MV)

Clinical Unit of Pharmacy, University Hospital Virgen del Rocio, 41013 Seville, Spain.

José Molina (J)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.

Jerónimo Pachón (J)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.
Department of Medicine, University of Seville, 41004 Seville, Spain.

José Miguel Cisneros (JM)

Infectious Diseases Research Group, Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocio, Avenue Manuel Siurot, 41013 Seville, Spain.
Department of Medicine, University of Seville, 41004 Seville, Spain.

Classifications MeSH