The Role of APP
APP
O-glycan
ppGalNAc-T
Journal
Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414
Informations de publication
Date de publication:
18 11 2020
18 11 2020
Historique:
received:
01
10
2020
revised:
16
11
2020
accepted:
16
11
2020
entrez:
21
11
2020
pubmed:
22
11
2020
medline:
7
9
2021
Statut:
epublish
Résumé
The number of people with dementia is increasing rapidly due to the increase in the aging population. Alzheimer's disease (AD) is a type of neurodegenerative dementia caused by the accumulation of abnormal proteins. Genetic mutations, smoking, and several other factors have been reported as causes of AD, but alterations in glycans have recently been demonstrated to play a role in AD. Amyloid-β (Aβ), a cleaved fragment of APP, is the source of senile plaque, a pathological feature of AD. APP has been reported to undergo
Identifiants
pubmed: 33218200
pii: biom10111569
doi: 10.3390/biom10111569
pmc: PMC7699271
pii:
doi:
Substances chimiques
Amyloid beta-Protein Precursor
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Japan Society for the Promotion of Science
ID : JP19K07883
Organisme : Japan Society for the Promotion of Science
ID : JP26460090
Références
Biochim Biophys Acta. 2012 Dec;1820(12):2079-94
pubmed: 23022508
Neuron. 1991 Apr;6(4):487-98
pubmed: 1673054
Clin Sci (Lond). 2019 May 21;133(10):1167-1184
pubmed: 31076460
Biochim Biophys Acta Gen Subj. 2017 Oct;1861(10):2462-2472
pubmed: 28711406
J Neurochem. 2006 Feb;96(4):924-33
pubmed: 16412100
J Biol Chem. 2010 Jun 18;285(25):19491-501
pubmed: 20371600
J Biol Chem. 2011 Apr 22;286(16):14493-507
pubmed: 21349845
Oncotarget. 2015 Mar 20;6(8):5650-65
pubmed: 25730904
Glycobiology. 2020 Oct 21;30(11):910-922
pubmed: 32304323
Nat Commun. 2016 Apr 05;7:11205
pubmed: 27046227
J Biol Chem. 2016 Nov 11;291(46):24041-24053
pubmed: 27687728
J Biol Chem. 1998 Mar 13;273(11):6277-84
pubmed: 9497354
J Biol Chem. 2014 Jun 20;289(25):17312-24
pubmed: 24798328
Science. 2001 Mar 23;291(5512):2376-8
pubmed: 11269319
Cell Signal. 2018 Jan;42:184-193
pubmed: 29097258
Nat Commun. 2011 Dec 13;2:583
pubmed: 22158438
Glycobiology. 2003 Jan;13(1):1R-16R
pubmed: 12634319
Cancer Genomics Proteomics. 2008 Nov-Dec;5(6):333-40
pubmed: 19287074
J Biol Chem. 2010 Nov 19;285(47):36293-303
pubmed: 20837471
J Biol Chem. 2010 Dec 17;285(51):40097-103
pubmed: 20952385
J Biol Chem. 2014 Nov 7;289(45):30977-89
pubmed: 25253695
J Biol Chem. 1994 Jul 1;269(26):17386-9
pubmed: 8021238
Sci Rep. 2017 Apr 10;7:46174
pubmed: 28393893
Biochem Biophys Res Commun. 2015 Nov 27;467(4):955-60
pubmed: 26471307
J Cell Sci. 1998 Jan;111 ( Pt 1):45-60
pubmed: 9394011
Nat Rev Neurosci. 2007 Jul;8(7):499-509
pubmed: 17551515
Nature. 2012 Aug 2;488(7409):96-9
pubmed: 22801501
Am J Cancer Res. 2018 Sep 01;8(9):1739-1751
pubmed: 30323967
J Biochem. 2017 Jan;161(1):99-111
pubmed: 28053144
J Biol Chem. 2014 Nov 7;289(45):30990-1000
pubmed: 25253696
Gene Expr Patterns. 2014 Sep;16(1):1-7
pubmed: 25026003
Glycobiology. 2003 Jul;13(7):549-57
pubmed: 12651884
Aging (Albany NY). 2020 Jun 18;12(12):11794-11811
pubmed: 32559179
Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3152-61
pubmed: 23912186
Glycobiology. 2016 Apr;26(4):360-76
pubmed: 26610890
J Proteomics. 2020 Oct 30;229:103966
pubmed: 32891889
J Cell Sci. 1996 May;109 ( Pt 5):999-1008
pubmed: 8743947
Glycobiology. 2012 Jun;22(6):736-56
pubmed: 22183981
J Biol Chem. 2017 Dec 29;292(52):21304-21319
pubmed: 29061849
Cancer Cell. 2017 Nov 13;32(5):639-653.e6
pubmed: 29136507
Cell. 1989 Apr 7;57(1):115-26
pubmed: 2649245
Alzheimers Res Ther. 2013 Oct 08;5(5):46
pubmed: 24103387
Biochem Biophys Res Commun. 2011 Jan 21;404(3):882-6
pubmed: 21182826
J Mass Spectrom. 2012 May;47(5):591-603
pubmed: 22576872
Glycobiology. 2012 Jun;22(6):768-77
pubmed: 22186971
Nat Neurosci. 2016 Jan;19(1):55-64
pubmed: 26642089
Neurobiol Aging. 2014 Jul;35(7):1779.e15-6
pubmed: 24529499
Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11848-53
pubmed: 21712440
Biochim Biophys Acta. 1999 Oct 18;1472(1-2):344-58
pubmed: 10572956
Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14623-8
pubmed: 26554003
Biochem Biophys Res Commun. 2017 Aug 19;490(2):486-491
pubmed: 28624365
FEBS Lett. 2013 Jun 27;587(13):2046-54
pubmed: 23684647
J Neurochem. 2014 Jun;129(5):756-69
pubmed: 24517464
J Biol Chem. 2011 Sep 16;286(37):32684-96
pubmed: 21768105
Anal Chem. 2020 Nov 3;92(21):14383-14392
pubmed: 32881480
Geriatr Gerontol Int. 2010 Jul;10 Suppl 1:S32-40
pubmed: 20590840
Glycobiology. 2018 Nov 1;28(11):841-848
pubmed: 30084948
Am J Cancer Res. 2018 Dec 01;8(12):2419-2435
pubmed: 30662801
Glycobiology. 2010 Jan;20(1):99-106
pubmed: 19776078
Oncotarget. 2016 Mar 8;7(10):11251-62
pubmed: 26848976
Nature. 2010 Aug 5;466(7307):707-13
pubmed: 20686565
J Histochem Cytochem. 2006 Mar;54(3):317-28
pubmed: 16260590
J Biol Chem. 2006 Jul 7;281(27):18370-7
pubmed: 16638743
J Inherit Metab Dis. 2017 Jul;40(4):569-586
pubmed: 28484880
Front Immunol. 2016 Apr 12;7:117
pubmed: 27148252
Cancer Res. 2010 Apr 1;70(7):2759-69
pubmed: 20215525
Nat Chem Biol. 2020 Mar;16(3):351-360
pubmed: 31932717
J Biol Chem. 2018 May 11;293(19):7408-7422
pubmed: 29559555
Glycoconj J. 2008 Nov;25(8):775-86
pubmed: 18521746
J Neurosci Res. 1995 Jun 1;41(2):270-8
pubmed: 7650762
J Biol Chem. 2009 Jul 24;284(30):20387-97
pubmed: 19460755
J Alzheimers Dis. 2015;44(1):261-75
pubmed: 25208619
Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25196-25202
pubmed: 31740596
Am J Hum Genet. 2014 Feb 6;94(2):161-75
pubmed: 24507773
Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9893-8
pubmed: 22566642
Lancet Neurol. 2016 Jul;15(8):857-868
pubmed: 27302364
Nature. 1992 Jun 11;357(6378):500-3
pubmed: 1608449
Glycobiology. 2012 May;22(5):602-15
pubmed: 22171061
Biochim Biophys Acta Gen Subj. 2019 May;1863(5):870-882
pubmed: 30797803
Brain. 2020 Apr 1;143(4):1114-1126
pubmed: 32293671
Biochemistry. 1999 Jul 27;38(30):9728-34
pubmed: 10423252
Annu Rev Biochem. 2011;80:825-58
pubmed: 21391816
J Cell Biol. 2010 May 31;189(5):843-58
pubmed: 20498016
Arch Biochem Biophys. 1996 Jul 15;331(2):177-86
pubmed: 8660696
J Cell Mol Med. 2009 Mar;13(3):574-88
pubmed: 18410522
EMBO J. 2013 May 15;32(10):1478-88
pubmed: 23584533
Neurosci Lett. 1996 Dec 27;221(1):57-60
pubmed: 9014180
Glycobiology. 2008 Nov;18(11):861-70
pubmed: 18669915
Glycobiology. 2009 Sep;19(9):958-70
pubmed: 19318519
Biochem J. 2016 Jan 1;473(1):21-30
pubmed: 26467158
J Bone Miner Res. 2007 Feb;22(2):235-42
pubmed: 17129170
Cell Metab. 2016 Aug 9;24(2):234-45
pubmed: 27508872
Glycobiology. 2017 Jan;27(1):3-49
pubmed: 27558841
J Biol Chem. 2010 Dec 31;285(53):41443-54
pubmed: 20961856
Nature. 2013 Dec 19;504(7480):456-9
pubmed: 24226769