Phenotypic Adaptation of
Pseudomonas aeruginosa
TonB dependent transporters
antibiotics
iron uptake
proteomic
siderophore
siderophore–antibiotic
vectorization
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
18 Nov 2020
18 Nov 2020
Historique:
received:
30
10
2020
revised:
12
11
2020
accepted:
15
11
2020
entrez:
21
11
2020
pubmed:
22
11
2020
medline:
22
11
2020
Statut:
epublish
Résumé
Iron acquisition pathways have often been considered to be gateways for the uptake of antibiotics into bacteria. Bacteria excrete chelators, called siderophores, to access iron. Antibiotic molecules can be covalently attached to siderophores for their transport into pathogens during the iron-uptake process.
Identifiants
pubmed: 33218210
pii: microorganisms8111820
doi: 10.3390/microorganisms8111820
pmc: PMC7699141
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Agence Nationale de la Recherche
ID : ANR-10-INSB-08-03
Organisme : FP7 Innovative Medicines Joint Undertaking
ID : 115525
Organisme : Association Vaincre la Mucoviscidose
ID : RF20160501642/1/1/64
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