Fetal dural sinus thrombosis: A systematic review.


Journal

Prenatal diagnosis
ISSN: 1097-0223
Titre abrégé: Prenat Diagn
Pays: England
ID NLM: 8106540

Informations de publication

Date de publication:
01 2021
Historique:
received: 08 07 2020
revised: 13 11 2020
accepted: 14 11 2020
pubmed: 22 11 2020
medline: 4 1 2022
entrez: 21 11 2020
Statut: ppublish

Résumé

Fetal dural sinus thrombosis (DST) is a rare condition. Although numerous case reports exist, the findings appear heterogenous and providing accurate patient counselling remains challenging. A systematic literature review was conducted in accordance with PRISMA guidance. Thirty-one studies including 78 patients were included in this review. No association with maternal or neonatal coagulopathy, infection or trauma was found. The average gestational age at diagnosis was 25 weeks (range 17-34 weeks). Approximately half of foetuses affected were female (48.7%); one quarter were male (25.6%) and one quarter had no sex stated (25.6%). Termination of pregnancy was chosen in 25.6% of cases (20/78). In continuing pregnancies,10.3% (6/58) experienced a perinatal death. Antenatally, the majority of lesions either decreased in size (38.5%) or completely resolved (32.7%). The neonatal or childhood outcome was normal in 88.0% of survivors (44/50). The average age at follow up was 16.4 months, ranging from birth to 6 years. This review found that 10% of DST cases experience in-utero or neonatal death. In survivors, the majority of cases reduce in size or completely resolve in pregnancy and 85% are reported to have a good outcome. However, further evidence is needed regarding long-term neurocognitive sequelae.

Identifiants

pubmed: 33219698
doi: 10.1002/pd.5869
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

248-257

Informations de copyright

© 2020 John Wiley & Sons, Ltd.

Références

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Auteurs

Adalina Sacco (A)

Institute for Women's Health, University College London, London, UK.
Fetal Medicine Unit, University College London Hospitals, London, UK.

Deepika Pannu (D)

Fetal Medicine Unit, University College London Hospitals, London, UK.

Fred Ushakov (F)

Fetal Medicine Unit, University College London Hospitals, London, UK.

Leigh Dyet (L)

Department of Neonatology, University College London Hospitals, London, UK.

Pranav Pandya (P)

Institute for Women's Health, University College London, London, UK.
Fetal Medicine Unit, University College London Hospitals, London, UK.

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