Predictors of recovery in children aged 6-59 months with uncomplicated severe acute malnutrition: a multicentre study.
Predictors
Ready-to-use therapeutic food
Recovery
Severe acute malnutrition
Journal
Public health nutrition
ISSN: 1475-2727
Titre abrégé: Public Health Nutr
Pays: England
ID NLM: 9808463
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
pubmed:
24
11
2020
medline:
30
10
2021
entrez:
23
11
2020
Statut:
ppublish
Résumé
To identify predictors of recovery in children with uncomplicated severe acute malnutrition (SAM). This is a secondary data analysis from an individual randomised controlled trial, where children with uncomplicated SAM were randomised to three feeding regimens, namely ready-to-use therapeutic food (RUTF) sourced from Compact India, locally prepared RUTF or augmented home-prepared foods, under two age strata (6-17 months and 18-59 months) for 16 weeks or until recovery. Three sets of predictors that could influence recovery, namely child, family and nutritional predictors, were analysed. Rural and urban slum areas of three states of India, namely Rajasthan, Delhi and Tamil Nadu. In total, 906 children (age: 6-59 months) were analysed to estimate the adjusted hazard ratio (AHR) using the Cox proportional hazard ratio model to identify various predictors. Being a female child (AHR: 1·269 (1·016, 1·584)), better employment status of the child's father (AHR: 1·53 (1·197, 1·95)) and residence in a rental house (AHR: 1·485 (1·137, 1·94)) increased the chances of recovery. No hospitalisation (AHR: 1·778 (1·055, 2·997)), no fever, (AHR: 2·748 (2·161, 3·494)) and ≤ 2 episodes of diarrhoea (AHR: 1·579 (1·035, 2·412)) during the treatment phase; availability of community-based peer support to mothers for feeding (AHR: 1·61 (1·237, 2·097)) and a better weight-for-height Z-score (WHZ) at enrolment (AHR: 1·811 (1·297, 2·529)) predicted higher chances of recovery from SAM. The probability of recovery increases in children with better WHZ and with the initiation of treatment for acute illnesses to avoid hospitalisation, availability of peer support and better employment status of the father.
Identifiants
pubmed: 33222710
pii: S1368980020004723
doi: 10.1017/S1368980020004723
doi:
Types de publication
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4899-4907Subventions
Organisme : World Health Organization
ID : 001
Pays : International