Predictors of recovery in children aged 6-59 months with uncomplicated severe acute malnutrition: a multicentre study.


Journal

Public health nutrition
ISSN: 1475-2727
Titre abrégé: Public Health Nutr
Pays: England
ID NLM: 9808463

Informations de publication

Date de publication:
10 2021
Historique:
pubmed: 24 11 2020
medline: 30 10 2021
entrez: 23 11 2020
Statut: ppublish

Résumé

To identify predictors of recovery in children with uncomplicated severe acute malnutrition (SAM). This is a secondary data analysis from an individual randomised controlled trial, where children with uncomplicated SAM were randomised to three feeding regimens, namely ready-to-use therapeutic food (RUTF) sourced from Compact India, locally prepared RUTF or augmented home-prepared foods, under two age strata (6-17 months and 18-59 months) for 16 weeks or until recovery. Three sets of predictors that could influence recovery, namely child, family and nutritional predictors, were analysed. Rural and urban slum areas of three states of India, namely Rajasthan, Delhi and Tamil Nadu. In total, 906 children (age: 6-59 months) were analysed to estimate the adjusted hazard ratio (AHR) using the Cox proportional hazard ratio model to identify various predictors. Being a female child (AHR: 1·269 (1·016, 1·584)), better employment status of the child's father (AHR: 1·53 (1·197, 1·95)) and residence in a rental house (AHR: 1·485 (1·137, 1·94)) increased the chances of recovery. No hospitalisation (AHR: 1·778 (1·055, 2·997)), no fever, (AHR: 2·748 (2·161, 3·494)) and ≤ 2 episodes of diarrhoea (AHR: 1·579 (1·035, 2·412)) during the treatment phase; availability of community-based peer support to mothers for feeding (AHR: 1·61 (1·237, 2·097)) and a better weight-for-height Z-score (WHZ) at enrolment (AHR: 1·811 (1·297, 2·529)) predicted higher chances of recovery from SAM. The probability of recovery increases in children with better WHZ and with the initiation of treatment for acute illnesses to avoid hospitalisation, availability of peer support and better employment status of the father.

Identifiants

pubmed: 33222710
pii: S1368980020004723
doi: 10.1017/S1368980020004723
doi:

Types de publication

Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4899-4907

Subventions

Organisme : World Health Organization
ID : 001
Pays : International

Auteurs

Sam Marconi David (SM)

Department of Community Health, Christian Medical College, Vellore, TN, India.

Preethi N Ragasudha (PN)

Department of Community Health, Christian Medical College, Vellore, TN, India.

Sunita Taneja (S)

Centre for Health Research and Development, Society for Applied Studies, New Delhi, India.

Sanjana Brahmawar Mohan (SB)

Sitaram Bhartia Institute of Science and Research, New Delhi, India.

Sharad D Iyengar (SD)

Action Research and Training for Health, Udaipur, Rajasthan, India.

Ruby Angeline Pricilla (RA)

Department of Community Health, Christian Medical College, Vellore, TN, India.

Jose Martines (J)

Centre for Intervention Science in Maternal and Child Health, Centre for International Health, University of Bergen, Bergen, Norway.

Harshpal Singh Sachdev (HS)

Sitaram Bhartia Institute of Science and Research, New Delhi, India.

Virendra Suhalka (V)

Action Research and Training for Health, Udaipur, Rajasthan, India.

Venkata Raghava Mohan (VR)

Department of Community Health, Christian Medical College, Vellore, TN, India.

Sarmila Mazumder (S)

Centre for Health Research and Development, Society for Applied Studies, New Delhi, India.

Ranadip Chowdhury (R)

Centre for Health Research and Development, Society for Applied Studies, New Delhi, India.

Rajiv Bahl (R)

Department of Maternal, Newborn, Child and Adolescent Health, World Health Organisation, Geneva, Switzerland.

Anuradha Bose (A)

Department of Community Health, Christian Medical College, Vellore, TN, India.

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