Seminal Plasma Triggers the Differential Expression of the Glucocorticoid Receptor (

RT-qPCR female genital tract gene expression glucocorticoid receptor rabbit seminal plasma

Journal

Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614

Informations de publication

Date de publication:
19 Nov 2020
Historique:
received: 02 10 2020
revised: 05 11 2020
accepted: 16 11 2020
entrez: 24 11 2020
pubmed: 25 11 2020
medline: 25 11 2020
Statut: epublish

Résumé

Rabbits are interesting as research animal models for reproduction, due to their condition of species of induced ovulation, with the release of endogenous gonadotropin-releasing hormone (GnRH) due to coitus. Glucocorticoid (GC) signaling, crucial for physiological homeostasis, is mediated through a yet unclear mechanism, by the GC receptor (NR3C1/GR). After mating, the female reproductive tract undergoes dynamic modifications, triggered by gene transcription, a pre-amble for fertilization and pregnancy. This study tested the hypothesis that when ovulation is induced, the expression of

Identifiants

pubmed: 33228207
pii: ani10112158
doi: 10.3390/ani10112158
pmc: PMC7699521
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Svenska Forskningsrådet Formas
ID : Project 2017-00946 and Project 2019-00288
Organisme : Vetenskapsrådet
ID : Project 2015-05919
Organisme : Ministerio de Ciencia e Innovación
ID : IJDC-2015-24380
Organisme : Generalitat de Catalunya
ID : FI_B 00236
Organisme : Ministerio de Educación, Cultura y Deporte
ID : FPU15/06029
Organisme : Fundación Séneca
ID : 20780/PD/18

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Auteurs

Mateo Ruiz-Conca (M)

Department of Biomedical and Clinical Sciences (BKV), Division of Children's and Women Health (BKH), Obstetrics and Gynecology, Linköping University, 58185 Linköping, Sweden.
Department of Animal Health and Anatomy, Veterinary Faculty, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.

Jaume Gardela (J)

Department of Biomedical and Clinical Sciences (BKV), Division of Children's and Women Health (BKH), Obstetrics and Gynecology, Linköping University, 58185 Linköping, Sweden.
Department of Animal Health and Anatomy, Veterinary Faculty, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.

Amaia Jauregi-Miguel (A)

Department of Biomedical and Clinical Sciences (BKV), Division of Molecular Medicine and Virology (MMV), Linköping University, 58185 Linköping, Sweden.

Cristina A Martinez (CA)

Department of Biomedical and Clinical Sciences (BKV), Division of Children's and Women Health (BKH), Obstetrics and Gynecology, Linköping University, 58185 Linköping, Sweden.

Heriberto Rodríguez-Martinez (H)

Department of Biomedical and Clinical Sciences (BKV), Division of Children's and Women Health (BKH), Obstetrics and Gynecology, Linköping University, 58185 Linköping, Sweden.

Manel López-Béjar (M)

Department of Animal Health and Anatomy, Veterinary Faculty, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
College of Veterinary Medicine, Western University of Health Sciences, Pomona, CA 91766, USA.

Manuel Alvarez-Rodriguez (M)

Department of Biomedical and Clinical Sciences (BKV), Division of Children's and Women Health (BKH), Obstetrics and Gynecology, Linköping University, 58185 Linköping, Sweden.
Department of Animal Health and Anatomy, Veterinary Faculty, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.

Classifications MeSH