Pulmonary Manifestations of Systemic Vasculitis in Children.
Child
Lung
Pulmonary features
Vasculitis
Journal
Pediatric clinics of North America
ISSN: 1557-8240
Titre abrégé: Pediatr Clin North Am
Pays: United States
ID NLM: 0401126
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
entrez:
24
11
2020
pubmed:
25
11
2020
medline:
27
4
2021
Statut:
ppublish
Résumé
Vasculitides are defined according to the vessel size involved, and they tend to affect certain organ systems. Pulmonary involvement is rare in the common childhood vasculitides, such as Kawasaki disease, IgA vasculitis (Henoch Schonlein purpura). On the other hand, lung involvement is common in a rare pediatric vasculitis, granulomatosis with polyangiitis (GPA) (Wegener granulomatosis), where respiratory system findings are common. A criterion in the Ankara 2008 classification criteria for GPA is the presence of nodules, cavities, or fixed infiltrates. The adult data suggest that rituximab may be an alternative to cyclophosphamide in induction treatment.
Identifiants
pubmed: 33228930
pii: S0031-3955(20)30136-X
doi: 10.1016/j.pcl.2020.09.014
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
167-176Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure The authors have nothing to disclose related to this work. However, Dr S. Ozen has received consultation and speaker fees from Novartis and SOBI.