Epithelial remodelling masquerading as keratoconus progression: An interesting case report.
Epithelial remodeling
keratoconus
progression
trehalose
Journal
Indian journal of ophthalmology
ISSN: 1998-3689
Titre abrégé: Indian J Ophthalmol
Pays: India
ID NLM: 0405376
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
entrez:
24
11
2020
pubmed:
25
11
2020
medline:
15
5
2021
Statut:
ppublish
Résumé
A 25-year-old male patient presented with chief complaints of itching in both eyes (OU) for the past one month. Detailed ophthalmic examination showed best-corrected visual acuity of 6/6 OU. On slit-lamp examination of the left eye, Vogt's striae were documented and rest of the anterior segment was normal OU. Pentacam-HR and ASOCT confirmed the diagnosis of keratoconus. The patient was started on Trehalose containing preparation for both eyes. On follow-up visit at 8 months, progression was documented on Pentacam-HR. MS-39 showed epithelial remodeling, but no stromal or posterior elevation, indicative of a pseudo-progression. Corneal epithelial remodeling post topical trehalose containing eye drops application has been very sparsely reported in literature. It is an important differential to consider when faced with a situation of a likely progression of keratoconus, especially to differentiate true from pseudo-progression.
Identifiants
pubmed: 33229704
pii: IndianJOphthalmol_2020_68_12_3053_301256
doi: 10.4103/ijo.IJO_2554_20
pmc: PMC7856944
doi:
Substances chimiques
Ophthalmic Solutions
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
3053-3057Déclaration de conflit d'intérêts
None
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