Postpartum health risks among women with hypertensive disorders of pregnancy, California 2008-2012.


Journal

Journal of hypertension
ISSN: 1473-5598
Titre abrégé: J Hypertens
Pays: Netherlands
ID NLM: 8306882

Informations de publication

Date de publication:
01 05 2021
Historique:
pubmed: 25 11 2020
medline: 16 10 2021
entrez: 24 11 2020
Statut: ppublish

Résumé

The aim of this study was to understand the associations between hypertensive disorders of pregnancy (HDP) and postpartum complications throughout the newly defined 12-week postpartum transition. We conducted a retrospective cohort study of the associations of HDP (any/subtype) with postpartum complications among 2.5 million California births, 2008-2012. We identified complications from discharge diagnoses from maternal hospital encounters (emergency department visits and readmissions) in the 12 weeks after giving birth. We compared rates of complications, overall and by diagnostic category, between groups defined by HDP. In survival analyses, we calculated the adjusted hazard ratios of postpartum complications associated with HDP. We adjusted for maternal age, race/ethnicity, prepregnancy obesity, chronic diabetes, gestational diabetes, insurance, delivery mode, gestational age and birth outcome (term and size). Among women with and without HDP, 12.8 and 7.7%, respectively, had a hospital encounter within 12 weeks of giving birth [adjusted hazard ratio 1.5, 95% confidence interval (95% CI): 1.5-1.5]. HDP was associated with increased risk across all major categories of complications: hypertension-related, adjusted hazard ratio 11.8 (95% CI: 11.2-12.3); childbirth-related, 1.4 (1.3-1.4); and other, 1.4 (1.4-1.4). Risk of any complication differed by hypertensive subtype: chronic hypertension with super-imposed preeclampsia, adjusted hazard ratio 1.8 (95% CI: 1.7-1.8); chronic hypertension, 1.6 (1.6-1.7); preeclampsia/eclampsia, 1.3 (1.3-1.4); and gestational hypertension, 1.2 (1.2-1.3). Over a quarter (28.9%) of maternal hospital encounters occurred more than 6 weeks after giving birth; this did not differ substantially by HDP status. Women with HDP are at an increased risk for virtually all postpartum complications, including those not related to hypertension, and may benefit from enhanced and comprehensive postpartum care.

Identifiants

pubmed: 33230021
pii: 00004872-202105000-00026
doi: 10.1097/HJH.0000000000002711
pmc: PMC8564993
mid: NIHMS1744886
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1009-1017

Subventions

Organisme : NICHD NIH HHS
ID : R00 HD079658
Pays : United States
Organisme : NIMHD NIH HHS
ID : R01 MD013648
Pays : United States
Organisme : NINR NIH HHS
ID : R01 NR017020
Pays : United States

Informations de copyright

Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

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Auteurs

Mara E Murray Horwitz (ME)

Department of Population Medicine, Harvard Pilgrim Healthcare Institute and Harvard Medical School, Boston, Massachusetts.

Maria I Rodriguez (MI)

Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon.

Mekhala Dissanayake (M)

Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon.

Suzan L Carmichael (SL)

Departments of Pediatrics and Obstetrics & Gynecology, Stanford University School of Medicine, Palo Alto, California.

Jonathan M Snowden (JM)

Department of Obstetrics & Gynecology, Oregon Health & Science University and School of Public Health, Oregon Health & Science University-Portland State University, Portland, Oregon, USA.

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