Mechanical testing of glutaraldehyde cross-linked mitral valves. Part one: In vitro mechanical behaviour.

Animals Bioprosthesis Glutaral Heart Valve Prosthesis Mechanical Tests Mitral Valve Swine
Cross-linking glutaraldehyde in vitro mechanical behaviour mechanics mitral valve

Journal

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
ISSN: 2041-3033
Titre abrégé: Proc Inst Mech Eng H
Pays: England
ID NLM: 8908934

Informations de publication

Date de publication:
Mar 2021
Historique:
pubmed: 25 11 2020
medline: 19 8 2021
entrez: 24 11 2020
Statut: ppublish

Résumé

The aim of this study was to perform an initial assessment, in vitro, of the feasibility of using a glutaraldehyde cross-linked porcine mitral valve to retain acute functionality, focusing on assessing mitral regurgitation. Six porcine hearts were tested using an in vitro simulator. Testing was repeated following cross-linking of mitral valves; where cross-linking was achieved by placing them in a glutaraldehyde solution. The simulator enabled systolic pressure on the ventricular side of the valve to be mimicked. Following testing, mitral valve leaflets underwent Scanning Electron Microscopy of the ventricular surface of both the anterior and posterior leaflets (1 cm

Identifiants

DOI: 10.1177/0954411920975894 PMID: 33231114
pubmed: 33231114
doi: 10.1177/0954411920975894
doi:

Substances chimiques

Glutaral T3C89M417N

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

281-290

Auteurs

Rhiannon Northeast (R)

Department of Mechanical Engineering, University of Birmingham, Birmingham, UK.

Matthew Constable (M)

Department of Mechanical Engineering, University of Birmingham, Birmingham, UK.

Hanna E Burton (HE)

Department of Mechanical Engineering, University of Birmingham, Birmingham, UK.

Bernard M Lawless (BM)

Department of Mechanical Engineering, University of Birmingham, Birmingham, UK.
Filament PD, Level 4 - Skypark 3, Skypark, Glasgow, UK.

Vera Gramigna (V)

University of Magna Graecia, Catanzaro, Italy.
IBFM, National Research Council, Germaneto, Catanzaro, Italy.

Kheng Lim Goh (K)

Department of Mechanical Engineering, University of Newcastle, Singapore.

Keith G Buchan (KG)

Department of Cardio-thoracic Surgery, Aberdeen Royal Infirmary, Forresterhill, Aberdeen, UK.

Daniel M Espino (DM)

Department of Mechanical Engineering, University of Birmingham, Birmingham, UK.
ORCID: 0000-0001-7608-5619

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Mechanical testing of glutaraldehyde...
questionsmedicales.fr › Équipement et fournitures › Prothèses et implants › Bioprothèse › Mechanical testing of glutaraldehyde...
questionsmedicales.fr › Composés chimiques organiques › Aldéhydes › Glutaraldéhyde › Mechanical testing of glutaraldehyde...
questionsmedicales.fr › Équipement et fournitures › Prothèses et implants › Prothèse valvulaire cardiaque › Mechanical testing of glutaraldehyde...
questionsmedicales.fr › Techniques d'investigation › Test de matériaux › Essais Mécaniques › Mechanical testing of glutaraldehyde...
questionsmedicales.fr › Système cardiovasculaire › Coeur › Valves cardiaques › Valve atrioventriculaire gauche › Mechanical testing of glutaraldehyde...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Mechanical testing of glutaraldehyde...