Multi-wavelength, handheld laser speckle imaging for skin evaluation.
basal cell carcinoma
handheld
laser speckle imaging
non-invasive human skin diagnostics
skin ageing
Journal
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
ISSN: 1600-0846
Titre abrégé: Skin Res Technol
Pays: England
ID NLM: 9504453
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
31
07
2020
accepted:
07
09
2020
pubmed:
25
11
2020
medline:
19
8
2021
entrez:
24
11
2020
Statut:
ppublish
Résumé
A handheld device was developed and qualified for in vivo human skin evaluation using laser speckle imaging technology. Each laser speckle device prototype allows the choice of up to three different laser wavelengths in the range of 400 nm to 800 nm in total. Speckle pattern analysis gives various speckle parameters, for example, speckle contrast, speckle size, speckle modulation or fractal dimension. The developed laser speckle device prototypes were evaluated investigating three skin issues. We receive reproducible results from the speckle imaging device. For skin ageing, we found significant changes within three age groups. The effect of a methyl nicotinate treatment was clearly visible and quantifiable using a moorFLPI device as well as our speckle imaging device. In terms of basal cell carcinoma diagnosis, we found significant differences between normal and diseased skin, even though the number of samples was limited. As shown with first application examples, it was possible to demonstrate the potential of the method for skin evaluation in vivo.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
486-493Subventions
Organisme : Bundesministerium für Bildung und Forschung
ID : 13N13840-4
Informations de copyright
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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