Metabolites in the TCA Cycle Promote Resistance to Chloramphenicol of


Journal

Journal of proteome research
ISSN: 1535-3907
Titre abrégé: J Proteome Res
Pays: United States
ID NLM: 101128775

Informations de publication

Date de publication:
01 01 2021
Historique:
pubmed: 25 11 2020
medline: 22 6 2021
entrez: 24 11 2020
Statut: ppublish

Résumé

Antibiotic-resistant bacteria are a serious threat to human and animal health. Metabolite-enabled eradication of drug-resistant pathogens is an attractive strategy, and metabolite adjuvants, such as fumarate, are used for restoring the bactericidal ability of antibiotics. However, we show that metabolites in the TCA cycle increase the viability of

Identifiants

pubmed: 33231461
doi: 10.1021/acs.jproteome.0c00725
doi:

Substances chimiques

Anti-Bacterial Agents 0
Chloramphenicol 66974FR9Q1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

972-981

Auteurs

Chao Wang (C)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.
Shandong Provincial Key Laboratory of Freshwater Genetics and Breeding, Jinan 250013, China.

Xue-Sa Dong (XS)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.
Shandong Provincial Key Laboratory of Freshwater Genetics and Breeding, Jinan 250013, China.

Yan-Yan Yang (YY)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.

Guo-Jing Xu (GJ)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.

Meng-Meng Wu (MM)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.

Fa-Jun Yan (FJ)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.

Long-Gang Zhang (LG)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.
Shandong Provincial Key Laboratory of Freshwater Genetics and Breeding, Jinan 250013, China.

Li An (L)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.
Shandong Provincial Key Laboratory of Freshwater Genetics and Breeding, Jinan 250013, China.

Pei-Sheng Fu (PS)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.
Shandong Provincial Key Laboratory of Freshwater Genetics and Breeding, Jinan 250013, China.

Xi-Rong Wang (XR)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.
Shandong Provincial Key Laboratory of Freshwater Genetics and Breeding, Jinan 250013, China.

Yu-Bin Su (YB)

Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Department of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

Qing-Lei Meng (QL)

Shandong Freshwater Fisheries Research Institute, Jinan 250013, China.
Shandong Provincial Key Laboratory of Freshwater Genetics and Breeding, Jinan 250013, China.

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Classifications MeSH