Metabolites in the TCA Cycle Promote Resistance to Chloramphenicol of
Edwardsiella tarda
TCA cycle
antibiotic resistance
chloramphenicol
redox
Journal
Journal of proteome research
ISSN: 1535-3907
Titre abrégé: J Proteome Res
Pays: United States
ID NLM: 101128775
Informations de publication
Date de publication:
01 01 2021
01 01 2021
Historique:
pubmed:
25
11
2020
medline:
22
6
2021
entrez:
24
11
2020
Statut:
ppublish
Résumé
Antibiotic-resistant bacteria are a serious threat to human and animal health. Metabolite-enabled eradication of drug-resistant pathogens is an attractive strategy, and metabolite adjuvants, such as fumarate, are used for restoring the bactericidal ability of antibiotics. However, we show that metabolites in the TCA cycle increase the viability of
Identifiants
pubmed: 33231461
doi: 10.1021/acs.jproteome.0c00725
doi:
Substances chimiques
Anti-Bacterial Agents
0
Chloramphenicol
66974FR9Q1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM