A case report of gastrointestinal histoplasmosis in a patient treated with infliximab.
Case report
Gastrointestinal histoplasmosis
Infliximab
Journal
Clinical journal of gastroenterology
ISSN: 1865-7265
Titre abrégé: Clin J Gastroenterol
Pays: Japan
ID NLM: 101477246
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
20
02
2020
accepted:
06
11
2020
pubmed:
25
11
2020
medline:
29
6
2021
entrez:
24
11
2020
Statut:
ppublish
Résumé
Histoplasmosis is an endemic mycosis in some areas of North and South America. This disease is usually asymptomatic, but it can result in severe and disseminated infection involving gastrointestinal tract, especially in immunocompromised individuals. We report a case of a 33-years-old Ecuadorian male treated with infliximab who developed disseminated histoplasmosis with gastrointestinal affection. Due to the non-specific presentation of gastrointestinal histoplasmosis, the diagnosis is often delayed and it causes poor outcomes. It is important to consider this diagnosis in immunocompromised patients with compatible symptoms, like patients on TNF inhibitors.
Identifiants
pubmed: 33231849
doi: 10.1007/s12328-020-01298-y
pii: 10.1007/s12328-020-01298-y
doi:
Substances chimiques
Infliximab
B72HH48FLU
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
690-692Références
Kauffman CA. Histoplasmosis: a clinical and laboratory update. Clin Microbiol Rev. 2007;20:115–32.
doi: 10.1128/CMR.00027-06
Anstead G, Bicanic T, Arathoon E, et al. Histoplasmosis, blastomycosis, coccidioidomycosis, and cryptococcosis. In: Tropical infectious diseases. 3rd ed. Amsterdam: Elsevier Inc; 2011.
Ling Q, Zhu W, Lu Q, et al. Disseminated histoplasmosis in an immunocompetent patient from an endemic area: a case report. Medicine. 2018;97:e11486.
doi: 10.1097/MD.0000000000011486
Mandavdhare HS, et al. Gastointestinal histoplasmosis: a case series from a non-endemic region in North India. Intest Res. 2019;17:149–52.
doi: 10.5217/ir.2018.00111
Assi MA, Sandid MS, Baddour LM, et al. Systemic histoplasmosis: a 15-year retrospective institutional review of 111 patients. Medicine (Baltimore). 2007;86:162–9.
doi: 10.1097/md.0b013e3180679130
Fernández C, Illnait M, Martinez G, et al. Una actualización acerca de histoplasmosis. Rev Cubana Med Trop. 2011;63:189–205.
Zhu LL, Wang J, Wang YP, et al. Intestinal histoplasmosis in immunocompetent adults. World J Gastroenterol. 2016;22:4027–33.
doi: 10.3748/wjg.v22.i15.4027
Bhinder J, Mori A, Cao W, et al. A case of isolated gastrointestinal histoplasmosis. Cureus. 2018;10:e2951.
pubmed: 30210949
pmcid: 6130590
Rowe K, Green M, Nehme F, et al. Isolated ileal stricture secondary to Antigen-Negative GI Histoplasmosis in a Patient on Immunosuppressive therapy. ACG Case Rep J. 2017;4:e10.
doi: 10.14309/crj.2017.10
Gupta N, Fox C, Grisolano S, et al. Disseminated histoplasmosis with colonic ulcers in a patient receiving infliximab. Gastrointest Endosc. 2009;70:597–8.
doi: 10.1016/j.gie.2009.01.006
Wallis RS, Broder MS, Wong JY, et al. Granulomatous infectious diseases associated with tumor necrosis factor antagonists. Clin Infect Dis. 2004;38:1261–5.
doi: 10.1086/383317
Goulet CK, Moseley RH, Tonnerre C, et al. Clinical problem-solving. The unturned stone. N Engl J Med. 2005;352:489.
doi: 10.1056/NEJMcps041569
Guimaraes AJ, Nosanchuk JD, Zancopé-Oliveira RM, et al. Diagnosis of histoplasmosis. Braz J Microbiol. 2006;37:1–13.
doi: 10.1590/S1517-83822006000100001
Oladele RO, Ayanlowo OO, Richardson MD, et al. Histoplasmosis in Africa: an emerging or a neglected disease? PLOS Negl Trop Dis. 2018;12:1–17.
doi: 10.1371/journal.pntd.0006046