The effect of green Mediterranean diet on cardiometabolic risk; a randomised controlled trial.

cardiac risk factors and prevention metabolic syndrome obesity

Journal

Heart (British Cardiac Society)
ISSN: 1468-201X
Titre abrégé: Heart
Pays: England
ID NLM: 9602087

Informations de publication

Date de publication:
11 Jun 2021
Historique:
received: 13 07 2020
revised: 29 09 2020
accepted: 07 10 2020
medline: 26 11 2020
pubmed: 26 11 2020
entrez: 25 11 2020
Statut: epublish

Résumé

A Mediterranean diet is favourable for cardiometabolic risk. To examine the residual effect of a green Mediterranean diet, further enriched with green plant-based foods and lower meat intake, on cardiometabolic risk. For the DIRECT-PLUS parallel, randomised clinical trial we assigned individuals with abdominal obesity/dyslipidaemia 1:1:1 into three diet groups: healthy dietary guidance (HDG), Mediterranean and green Mediterranean diet, all combined with physical activity. The Mediterranean diets were equally energy restricted and included 28 g/day walnuts. The green Mediterranean diet further included green tea (3-4 cups/day) and a Participants (n=294; age 51 years; body mass index 31.3 kg/m The green MED diet, supplemented with walnuts, green tea and Mankai and lower in meat/poultry, may amplify the beneficial cardiometabolic effects of Mediterranean diet. This study is registered under ClinicalTrials.gov Identifier no NCT03020186.

Sections du résumé

BACKGROUND BACKGROUND
A Mediterranean diet is favourable for cardiometabolic risk.
OBJECTIVE OBJECTIVE
To examine the residual effect of a green Mediterranean diet, further enriched with green plant-based foods and lower meat intake, on cardiometabolic risk.
METHODS METHODS
For the DIRECT-PLUS parallel, randomised clinical trial we assigned individuals with abdominal obesity/dyslipidaemia 1:1:1 into three diet groups: healthy dietary guidance (HDG), Mediterranean and green Mediterranean diet, all combined with physical activity. The Mediterranean diets were equally energy restricted and included 28 g/day walnuts. The green Mediterranean diet further included green tea (3-4 cups/day) and a
RESULTS RESULTS
Participants (n=294; age 51 years; body mass index 31.3 kg/m
CONCLUSIONS CONCLUSIONS
The green MED diet, supplemented with walnuts, green tea and Mankai and lower in meat/poultry, may amplify the beneficial cardiometabolic effects of Mediterranean diet.
TRIAL REGISTRATION NUMBER BACKGROUND
This study is registered under ClinicalTrials.gov Identifier no NCT03020186.

Identifiants

pubmed: 33234670
pii: heartjnl-2020-317802
doi: 10.1136/heartjnl-2020-317802
doi:

Banques de données

ClinicalTrials.gov
['NCT03020186']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1054-1061

Informations de copyright

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: IrS advises the nutritional committee of Hinoman, Ltd. All other authors have no relevant conflict of interest to disclose.

Auteurs

Gal Tsaban (G)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Department of Medicine, Soroka University Medical Center, Beer Sheva, Israel.

Anat Yaskolka Meir (A)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Ehud Rinott (E)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Hila Zelicha (H)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Alon Kaplan (A)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Aryeh Shalev (A)

Department of Cardiology, Soroka University Medical Center, Beer Sheva, Israel.

Amos Katz (A)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Assaf Rudich (A)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Amir Tirosh (A)

Division of Endocrinology, Diabetes and Metabolism, Sheba Medical Center at Tel Hashomer, Tel Hashomer, Israel.
Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA.

Ilan Shelef (I)

Division of Diagnostic and Interventional Imaging, Soroka University Medical Center, Beer Sheva, Israel.

Ilan Youngster (I)

Center for Microbiome Research, Yitzhak Shamir Medical Center Assaf Harofeh, Zerifin, Israel.
Tel Aviv University Sackler Faculty of Medicine, Tel Aviv, Israel.

Sharon Lebovitz (S)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Noa Israeli (N)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

May Shabat (M)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Dov Brikner (D)

Department of Medicine, Nuclear Research Centre Negev, Beer-Sheva, Israel.

Efrat Pupkin (E)

Department of Medicine, Nuclear Research Centre Negev, Beer-Sheva, Israel.

Michael Stumvoll (M)

Department of Medicine, Leipzig University, Leipzig, Germany.

Joachim Thiery (J)

University of Leipzig, Leipzig, Germany.

Uta Ceglarek (U)

Department of Medicine, Leipzig University, Leipzig, Germany.

John T Heiker (JT)

Department of Medicine, Leipzig University, Leipzig, Germany.

Antje Körner (A)

Department of Medicine, Leipzig University, Leipzig, Germany.

Kathrin Landgraf (K)

Department of Medicine, Leipzig University, Leipzig, Germany.

Martin von Bergen (M)

Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany.

Matthias Blüher (M)

Department of Medicine, Leipzig University, Leipzig, Germany.

Meir J Stampfer (MJ)

Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA.
Brigham and Women's Hospital Channing Division of Network Medicine, Boston, Massachusetts, USA.

Iris Shai (I)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel irish@bgu.ac.il.
Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA.

Classifications MeSH