Parity and the use of folic acid supplementation during pregnancy.
folic acid
parity
population study
pregnancy supplementation
Journal
BMJ nutrition, prevention & health
ISSN: 2516-5542
Titre abrégé: BMJ Nutr Prev Health
Pays: England
ID NLM: 101769223
Informations de publication
Date de publication:
2019
2019
Historique:
received:
21
01
2019
revised:
25
03
2019
accepted:
13
04
2019
entrez:
25
11
2020
pubmed:
19
5
2019
medline:
19
5
2019
Statut:
epublish
Résumé
Folic acid (FA) supplementation has long been recommended before and during pregnancy to reduce the risk of neural tube defects. Factors influencing adherence to FA supplementation have been extensively evaluated, but little is known on the effect of parity. This study comes to examine the association between parity and maternal use of FA prior to and during pregnancy. In this retrospective population-based study, we identified mothers (N=228 555) of all children (N=578 204) born between the years 2000 and 2016 among members of a large health provider in Israel. Data on FA supplementation purchases were obtained from centralised medical databases. The median (IQR) total dose of FA purchased 12 months prior to child birth among previously nulliparous women (120 mg, 48-240) was significantly (p<0.001) higher than the dose purchased by women with one (90 mg (39-202)) and two prior births (84 mg (36-182)). The dose was even lower in women for three or more prior births (75 mg (36-165)). Despite the overall increasing secular trend in FA purchases during the study period, the negative relationship with parity remained. Adherence to FA supplementation is negatively associated with parity. Women with increasing parity may be at higher risk for pregnancy complications associated with low FA levels. The results of this study may inform the design of interventions to specifically increase adherence to FA supplementations among multiparous women.
Identifiants
pubmed: 33235954
doi: 10.1136/bmjnph-2019-000024
pii: bmjnph-2019-000024
pmc: PMC7664500
doi:
Types de publication
Journal Article
Langues
eng
Pagination
30-34Informations de copyright
© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
BMJ. 2007 Mar 3;334(7591):464
pubmed: 17259187
JAMA. 2013 Feb 13;309(6):570-7
pubmed: 23403681
JAMA. 2011 Oct 12;306(14):1566-73
pubmed: 21990300
Int J Cardiol. 2011 Nov 3;152(3):345-9
pubmed: 20826019
CMAJ. 2002 Aug 6;167(3):237-40
pubmed: 12186167
J Public Health (Oxf). 2016 Mar;38(1):122-9
pubmed: 25733660
Paediatr Perinat Epidemiol. 2009 May;23(3):199-206
pubmed: 19775381
BMJ. 2015 Nov 24;351:h6198
pubmed: 26602789
Birth. 2010 Mar;37(1):37-43
pubmed: 20402720
PLoS One. 2014 Feb 19;9(2):e89354
pubmed: 24586711
Eur J Epidemiol. 2003;18(12):1143-6
pubmed: 14758871
MMWR Morb Mortal Wkly Rep. 2010 Aug 13;59(31):980-4
pubmed: 20703205
BMC Pregnancy Childbirth. 2009 Jul 22;9:31
pubmed: 19622174
Am J Clin Nutr. 2006 Nov;84(5):1134-41
pubmed: 17093167
Eur J Public Health. 2012 Dec;22(6):904-13
pubmed: 22109988
Isr Med Assoc J. 2017 Aug;19(8):494-498
pubmed: 28825768
BJOG. 2004 May;111(5):399-408
pubmed: 15104602
Nutrients. 2011 Mar;3(3):370-84
pubmed: 22254102
CMAJ. 1993 Nov 1;149(9):1239-43
pubmed: 8221478
N Engl J Med. 1992 Dec 24;327(26):1832-5
pubmed: 1307234
Prev Med. 2004 Oct;39(4):731-7
pubmed: 15351539
BJOG. 2013 Dec;120(13):1661-7
pubmed: 24034718
MMWR Recomm Rep. 2002 Sep 13;51(RR-13):1-3
pubmed: 12353506
J Nutr. 2002 Aug;132(8 Suppl):2356S-2360S
pubmed: 12163692
Int J Nurs Pract. 2018 Apr;24(2):e12622
pubmed: 29417703
Public Health Rep. 1990 May-Jun;105(3):264-7
pubmed: 2113685
Matern Child Health J. 2015 Sep;19(9):1974-84
pubmed: 25663654
J Am Coll Nutr. 1996 Apr;15(2):121-5
pubmed: 8778140
Can J Public Health. 2014 Jan 15;105(1):e40-6
pubmed: 24735696
Lancet. 1991 Jul 20;338(8760):131-7
pubmed: 1677062