Human microbiome and allergy.


Journal

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
ISSN: 1399-3038
Titre abrégé: Pediatr Allergy Immunol
Pays: England
ID NLM: 9106718

Informations de publication

Date de publication:
11 2020
Historique:
received: 22 07 2020
accepted: 04 08 2020
entrez: 25 11 2020
pubmed: 26 11 2020
medline: 19 8 2021
Statut: ppublish

Résumé

Human microbiome contributes to critical functions that impact health and disease. It influences the development of the immune system, and the pathogenesis of immunological disorders included allergy. While it is easy to understand how airway microbiome, influencing local inflammation and immune activity, could contribute to shaping asthma phenotype, it is not so obvious to understand the influence by the gut microbiome, but there is growing evidence about it. The increase of allergic disorders in western countries led to investigate the role environment is playing and how it may change our microbiome and immune system, with the hope of finding new preventive approaches for allergy.

Identifiants

pubmed: 33236419
doi: 10.1111/pai.13360
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5-7

Informations de copyright

© 2020 European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.

Références

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Lee KH, Song Y, Wu W, et al. The gut microbiota, environmental factors, and links to the development of food allergy. Clin Mol Allergy. 2020;18:5.
Ho H, Bunyavanich S. Role of the microbiome in food allergy. Curr Allergy Asthma Rep. 2018;18:27.
West CE, Jenmalm MC, Prescott SL. The gut microbiota and its role in the development of allergic disease: a wider perspective. Clin Exp Allergy. 2015;45:43-53.
Fanos V. Metabolomics and Microbiomics. Personalized Medicine from the Fetus to the Adult. London: Academic Press, Elsevier; 2016.
Fanos V. I Batteri Pionieri Pilastri Della Salute. Quartu S. Elena: Hygeia Press; 2020.
Jatzlauk G, Bartel S, Heine H, et al. Influences of environmental bacteria and their metabolites on allergies, asthma, and host microbiota. Allergy. 2017;72:1859-1867.
Lukacs NW, Huang YJ. Microbiota-immune interactions in asthma pathogenesis and phenotype. Curr Opin Immunol. 2020;66:22-26.
Li L, Han Z, Niu X, et al. Probiotic supplementation for prevention of atopic dermatitis in infants and children: a systematic review and meta-analysis. Am J Clin Dermatol. 2019;20:367-377.
Bawany F, Beck LA, Järvinen KM. Halting the March: primary prevention of atopic dermatitis and food allergies. J Allergy Clin Immunol Pract. 2020;8:860-875.

Auteurs

Vittoria Montecchiani (V)

School of Pediatrics, University of Cagliari, Cagliari, Italy.

Vassilios Fanos (V)

Neonatal Intensive Care Unit AOU, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.

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