Electrical storm in a patient with COVID-19 treated with hydroxychloroquine: A case report.

COVID-19 Electrical storm QTc prolongation case report hydroxychloroquine ventricular tachycardia

Journal

SAGE open medical case reports
ISSN: 2050-313X
Titre abrégé: SAGE Open Med Case Rep
Pays: England
ID NLM: 101638686

Informations de publication

Date de publication:
2020
Historique:
received: 08 09 2020
accepted: 27 10 2020
entrez: 26 11 2020
pubmed: 27 11 2020
medline: 27 11 2020
Statut: epublish

Résumé

Hydroxychloroquine (HCQ) is a widely used drug to treat patients with coronavirus disease 19 (COVID-19). Although evidence of its efficacy and safety remains limited and controversial, both cardiac and non-cardiac adverse events are known to be associated with its use. To our knowledge, electrical storm in patients with COVID-19, or in any case treated with HCQ, has not been reported. We report the case of a 78-year-old male with an implantable cardiac resynchronization defibrillator (CRT-D) and a non-severe form of COVID-19. After a few days of home therapy with HCQ, an electrical storm was revealed that was associated with an increase in QTc. Following admission to the intensive care unit, HCQ was discontinued and progressive reduction of the QTc with electrical stabilization was observed. This clinical case highlights the potential risk of arrythmia associated with the use of HCQ and stresses the need for close electrocardiographic monitoring, especially in patients with established heart disease.

Identifiants

pubmed: 33240503
doi: 10.1177/2050313X20974217
pii: 10.1177_2050313X20974217
pmc: PMC7675879
doi:

Types de publication

Case Reports

Langues

eng

Pagination

2050313X20974217

Informations de copyright

© The Author(s) 2020.

Déclaration de conflit d'intérêts

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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Auteurs

Francesco Vetta (F)

Saint Camillus International University of Health Sciences, Rome, Italy.

Leonardo Marinaccio (L)

Department of Cardiology, Immacolata Concezione Hospital, Piove di Sacco, Italy.

Giampaolo Vetta (G)

Saint Camillus International University of Health Sciences, Rome, Italy.

Domenico Marchese (D)

Department of Cardiology, Immacolata Concezione Hospital, Piove di Sacco, Italy.

Classifications MeSH