Regular physical activity postpones age of occurrence of first-ever stroke and improves long-term outcomes.
Death
Disability
Functional dependency
Physical activity
Population-based study
Recurrence
Stroke
Journal
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
30
09
2019
accepted:
11
11
2020
pubmed:
27
11
2020
medline:
10
8
2021
entrez:
26
11
2020
Statut:
ppublish
Résumé
Few data are available on the associations between the level of pre-stroke physical activity and long-term outcomes in patients with stroke. This study is designed to assess the associations between pre-stroke physical activity and age of first-ever stroke occurrence and long-term outcomes. Six hundred twenty-four cases with first-ever stroke were recruited from the Mashhad Stroke Incidence Study a prospective population-based cohort in Iran. Data on Physical Activity Level (PAL) were collected retrospectively and were available in 395 cases. According to the PAL values, subjects were classified as inactive (PAL < 1.70) and active (PAL ≥ 1.70). Age at onset of stroke was compared between active and inactive groups. Using logistic model, we assessed association between pre-stroke physical activity and long-term (5-year) mortality, recurrence, disability, and functional dependency rates. We used multiple imputation to analyze missing data. Inactive patients (PAL < 1.70) were more than 6 years younger at their age of first-ever-stroke occurrence (60.7 ± 15.5) than active patients (67.0 ± 13.2; p < 0.001). Patients with PAL< 1.7 also had a greater risk of mortality at 1 year [adjusted odds ratio (aOR) = 2.31; 95%CI: 1.14-4.67, p = 0.02] and 5 years after stroke (aOR = 1.81; 95%CI: 1.05-3.14, p = 0.03) than patients who were more physically active. Recurrence rate, disability, and functional dependency were not statistically different between two groups. Missing data analysis also showed a higher odds of death at one and 5 years for inactive patients. In our cohort, we observed a younger age of stroke and a higher odds of 1- and 5-year mortality among those with less physical activity. This is an important health promotion strategy to encourage people to remain physically active.
Identifiants
pubmed: 33241533
doi: 10.1007/s10072-020-04903-7
pii: 10.1007/s10072-020-04903-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3203-3210Subventions
Organisme : Mashhad University of Medical Sciences
ID : 85224
Informations de copyright
© 2020. Fondazione Società Italiana di Neurologia.
Références
Warburton DE, Nicol CW, Bredin SS (2006) Health benefits of physical activity: the evidence. CMAJ. 174(6):801–809
doi: 10.1503/cmaj.051351
Brach JS, FitzGerald S, Newman AB, Kelsey S, Kuller L, VanSwearingen JM et al (2003) Physical activity and functional status in community-dwelling older women: a 14-year prospective study. Arch Intern Med 163(21):2565–2571
doi: 10.1001/archinte.163.21.2565
Wendel-Vos G, Schuit A, Feskens E, Boshuizen H, Verschuren W, Saris W, Kromhout D (2004) Physical activity and stroke. A meta-analysis of observational data. Int J Epidemiol 33(4):787–798
doi: 10.1093/ije/dyh168
Durstine JL, Grandjean PW, Davis PG, Ferguson MA, Alderson NL, DuBose KD (2001) Blood lipid and lipoprotein adaptations to exercise. Sports Med 31(15):1033–1062
doi: 10.2165/00007256-200131150-00002
Huot M, Arsenault BJ, Gaudreault V, Poirier P, Pérusse L, Tremblay A, Bouchard C, Després JP, Rhéaume C (2011) Insulin resistance, low cardiorespiratory fitness, and increased exercise blood pressure: contribution of abdominal obesity. Hypertension. 58(6):1036–1042
doi: 10.1161/HYPERTENSIONAHA.111.180349
Colberg SR, Sigal RJ, Fernhall B, Regensteiner JG, Blissmer BJ, Rubin RR, Chasan-Taber L, Albright AL, Braun B (2010) Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement. Diabetes Care 33(12):e147–ee67
doi: 10.2337/dc10-9990
He X-f, Liu D-x, Zhang Q, Liang F-y, Dai G-y, Zeng J-s et al (2017) Voluntary exercise promotes glymphatic clearance of amyloid beta and reduces the activation of astrocytes and microglia in aged mice. Front Mol Neurosci 10:144
doi: 10.3389/fnmol.2017.00144
Binder DK, Scharfman HE (2004) Brain-derived neurotrophic factor. Growth Factors 22(3):123
doi: 10.1080/08977190410001723308
Siette J, Westbrook RF, Cotman C, Sidhu K, Zhu W, Sachdev P, Valenzuela MJ (2013) Age-specific effects of voluntary exercise on memory and the older brain. Biol Psychiatry 73(5):435–442
doi: 10.1016/j.biopsych.2012.05.034
Rist PM, Lee I-M, Kase CS, Gaziano JM, Kurth T (2011) Physical activity and functional outcomes from cerebral vascular events in men. Stroke. 42(12):3352–3356
doi: 10.1161/STROKEAHA.111.619544
Krarup L-H, Truelsen T, Gluud C, Andersen G, Zeng X, Korv J et al (2008) Prestroke physical activity is associated with severity and long-term outcome from first-ever stroke. Neurology. 71(17):1313–1318
doi: 10.1212/01.wnl.0000327667.48013.9f
Stroud N, Mazwi TML, Case LD, Brown RD, Brott TG, Worrall BB, Meschia JF, for the Ischemic Stroke Genetics Study Investigators (2009) Prestroke physical activity and early functional status after stroke. J Neurol Neurosurg Psychiatry 80(9):1019–1022
doi: 10.1136/jnnp.2008.170027
Wen CP, Liu CH, Jeng JS, Hsu SP, Chen CH, Lien LM, Chen AC, Lee JT, Chen PK, Hsu CS, Chern CM, Chen CC, Hsu MC, Lu K, Chen HJ, Wang HK, Muo CH, Hsu CY, Taiwan Stroke Registry Investigators (2017) Pre-stroke physical activity is associated with fewer post-stroke complications, lower mortality and a better long-term outcome. Eur J Neurol 24(12):1525–1531
doi: 10.1111/ene.13463
Diep L, Kwagyan J, Kurantsin-Mills J, Weir R, Jayam-Trouth A (2010) Association of physical activity level and stroke outcomes in men and women: a meta-analysis. J Women's Health 19(10):1815–1822
doi: 10.1089/jwh.2009.1708
Azarpazhooh MR, Etemadi MM, Donnan GA, Mokhber N, Majdi MR, Ghayour-Mobarhan M, Ghandehary K, Farzadfard MT, Kiani R, Panahandeh M, Thrift AG (2010) Excessive incidence of stroke in Iran: evidence from the Mashhad stroke incidence study (MSIS), a population-based study of stroke in the Middle East. Stroke. 41(1):e3–e10
doi: 10.1161/STROKEAHA.109.559708
Saber H, Thrift AG, Kapral MK, Shoamanesh A, Amiri A, Farzadfard MT, Behrouz R, Azarpazhooh MR (2017) Incidence, recurrence, and long-term survival of ischemic stroke subtypes: a population-based study in the Middle East. Int J Stroke 12(8):835–843
doi: 10.1177/1747493016684843
Salehi M, Amiri A, Thrift AG, Kapral MK, Sposato L, Behrouz R, Fang J, Shoeibi A, Hashemi P, Farzadfard MT, Mokhber N, Azarpazhooh MR (2018) Five-year recurrence rate and the predictors following stroke in the Mashhad stroke incidence study: a population-based cohort study of stroke in the Middle East. Neuroepidemiology. 50(1–2):18–22
doi: 10.1159/000485509
Farzadfard MT, Thrift AG, Amiri A, Kapral MK, Hashemi P, Sposato LA, Salehi M, Shoeibi A, Hoseini A, Mokhber N, Azarpazhooh MR (2018) Five-year case fatality following first-ever stroke in the Mashhad stroke incidence study: a population-based study of stroke in the Middle East. J Stroke Cerebrovasc Dis 27(4):1085–1089
doi: 10.1016/j.jstrokecerebrovasdis.2017.11.018
Hatano S (1976) Experience from a multicentre stroke register: a preliminary report. Bull World Health Organ 54(5):541–553
pubmed: 1088404
pmcid: 2366492
Lyden P, Brott T, Tilley B, Welch K, Mascha E, Levine S et al (1994) Improved reliability of the NIH stroke scale using video training. NINDS TPA stroke study group. Stroke 25(11):2220–2226
doi: 10.1161/01.STR.25.11.2220
Bolton-Smith C, Woodward M, Tunstall-Pedoe H (1992) The Scottish heart health study. Dietary intake by food frequency questionnaire and odds ratios for coronary heart disease risk. II. The antioxidant vitamins and fibre. Eur J Clin Nutr 46(2):85–93
pubmed: 1313760
Schofield W (1985) Predicting basal metabolic rate, new standards and review of previous work. Hum Nutr Clin Nutr 39:5–41
pubmed: 4044297
Joint F, Organization WH (1985) Energy and protein requirements: report of a Joint FAO/WHO/UNU Expert Consultation [held in Rome from 5 to 17 October 1981]: World Health Organization
Joint F (2004) Human energy requirements. Report of a Joint FAO/WHO/UNU Expert Consultation, Rome, 17–24 October 2001
Farzadfard MT, Sheikh Andalibi MS, Thrift AG, Morovatdar N, Stranges S, Amiri A, Kapral MK, Behrouz R, Juibary AG, Mokhber N, Azarpazhooh MR (2019) Long-term disability after stroke in Iran: evidence from the Mashhad stroke incidence study. Int J Stroke 14(1):44–47
doi: 10.1177/1747493018789839
Deplanque D, Masse I, Lefebvre C, Libersa C, Leys D, Bordet R (2006) Prior TIA, lipid-lowering drug use, and physical activity decrease ischemic stroke severity. Neurology. 67(8):1403–1410
doi: 10.1212/01.wnl.0000240057.71766.71
Stranahan AM, Zhou Y, Martin B, Maudsley S (2009) Pharmacomimetics of exercise: novel approaches for hippocampally-targeted neuroprotective agents. Curr Med Chem 16(35):4668–4678
doi: 10.2174/092986709789878292
Ekelund U, Steene-Johannessen J, Brown WJ, Fagerland MW, Owen N, Powell KE, Bauman A, Lee IM (2016) Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women. Lancet 388(10051):1302–1310
doi: 10.1016/S0140-6736(16)30370-1
Van Uffelen JG, Wong J, Chau JY, Van Der Ploeg HP, Riphagen I, Gilson ND et al (2010) Occupational sitting and health risks: a systematic review. Am J Prev Med 39(4):379–388
doi: 10.1016/j.amepre.2010.05.024
Yang L, Cao C, Kantor ED, Nguyen LH, Zheng X, Park Y, Giovannucci EL, Matthews CE, Colditz GA, Cao Y (2019) Trends in sedentary behavior among the US population, 2001-2016. JAMA. 321(16):1587–1597
doi: 10.1001/jama.2019.3636
Murphy MH, Donnelly P, Breslin G, Shibli S, Nevill AM (2013) Does doing housework keep you healthy? The contribution of domestic physical activity to meeting current recommendations for health. BMC Public Health 13(1):966
doi: 10.1186/1471-2458-13-966