Predictors of laboratory-positive COVID-19 in children and teenagers.
Adolescent
COVID-19
Child
Odds ratio
Real-time polymerase chain reaction
Journal
Public health
ISSN: 1476-5616
Titre abrégé: Public Health
Pays: Netherlands
ID NLM: 0376507
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
15
07
2020
revised:
07
10
2020
accepted:
12
10
2020
pubmed:
28
11
2020
medline:
2
1
2021
entrez:
27
11
2020
Statut:
ppublish
Résumé
The aim of the study was to identify factors predicting laboratory-positive coronavirus disease 2019 (COVID-19) in pediatric patients with acute respiratory symptoms. We conducted a cross-sectional analysis of a prospective cohort study. Data from 1849 individuals were analyzed. COVID-19 was confirmed (reverse transcription-quantitative polymerase chain reaction) in 15.9% of patients, and factors predicting a positive test result were evaluated through prevalence odds ratios and 95% confidence intervals. Increasing age, personal history of obesity, and household contact with a case were found to be associated, in the multiple regression model, with increased odds of a positive test result. Young patients residing in areas with higher population sizes, as well as those with severe respiratory symptoms, were less likely to be laboratory confirmed. Early identification and isolation of children and teenagers with suggestive symptoms of COVID-19 is important to limit viral spread. We identified several factors predicting the laboratory test result. Our findings are relevant from a public health policy perspective, particularly after the restart of in-person academic activities.
Identifiants
pubmed: 33246302
pii: S0033-3506(20)30454-6
doi: 10.1016/j.puhe.2020.10.012
pmc: PMC7584439
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
153-157Informations de copyright
Copyright © 2020 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.
Références
Lancet. 2020 Feb 15;395(10223):514-523
pubmed: 31986261
Am J Obstet Gynecol. 2020 Jun;222(6):521-531
pubmed: 32217113
Euro Surveill. 2020 Jan;25(3):
pubmed: 31992387
JAMA Pediatr. 2020 Sep 1;174(9):882-889
pubmed: 32320004
Epidemiol Infect. 2019 Jan;147:e183
pubmed: 31063113
J Immunol. 2017 May 15;198(10):4046-4053
pubmed: 28373583
BMJ. 2020 Apr 3;369:m1336
pubmed: 32245802
Front Immunol. 2015 Feb 24;6:76
pubmed: 25759691
Obesity (Silver Spring). 2020 Aug;28(8):1382-1385
pubmed: 32352652
Biol Sex Differ. 2010 Nov 05;1(1):6
pubmed: 21208466
Eur Respir J. 2020 Apr 23;55(4):
pubmed: 32241833
Diabetes Metab Syndr. 2020 Jul - Aug;14(4):469-471
pubmed: 32387864
Nature. 2020 May;581(7807):127-128
pubmed: 32382119
Lancet Infect Dis. 2020 Aug;20(8):911-919
pubmed: 32353347
Nutr Diabetes. 2017 Jun 5;7(6):e280
pubmed: 28581504
BMJ. 2020 May 29;369:m1996
pubmed: 32471884
Front Public Health. 2020 Apr 29;8:152
pubmed: 32411652