The IBD-disk Is a Reliable Tool to Assess the Daily-life Burden of Patients with Inflammatory Bowel Disease.
Crohn’s disease
disability
inflammatory bowel disease
patient-reported outcome
ulcerative colitis
Journal
Journal of Crohn's & colitis
ISSN: 1876-4479
Titre abrégé: J Crohns Colitis
Pays: England
ID NLM: 101318676
Informations de publication
Date de publication:
04 May 2021
04 May 2021
Historique:
pubmed:
28
11
2020
medline:
17
11
2021
entrez:
27
11
2020
Statut:
ppublish
Résumé
The inflammatory bowel disease [IBD]-disk is a 10-item self-questionnaire that is used to assess IBD-related disability. The aim of the present study was to evaluate this tool in the assessment of IBD daily-life burden. A 1-week cross-sectional study was conducted in 42 centres affiliated in France and Belgium. Patients were asked to complete the IBD-disk [best score: 0, worst score: 100] and a visual analogue scale [VAS] of IBD daily-life burden [best score: 0, worst score: 10]. Analyses included internal consistency, correlation analysis, and diagnostic performance assessment. Among the 2011 IBD outpatients who responded to the survey [67.8% of the patients had Crohn's disease], 49.9% were in clinical remission. The IBD-disk completion rate was 73.8%. The final analysis was conducted in this population [n = 1455 patients]. The mean IBD-disk score and IBD daily-life burden VAS were 39.0 ± 23.2 and 5.2 ± 2.9, respectively. The IBD-disk score was well correlated with the IBD daily-life burden VAS [r = 0.67; p <0.001]. At an optimal IBD-disk cut-off of 40, the area under the receiver operating characteristic curve [AUROC] for high IBD daily-life burden [VAS >5] was 0.81 (95% confidence interval [CI]: 0.79-0.83; p <0.001). In a large cohort of patients, the IBD-disk score was well correlated with IBD daily-life burden, and it could be used in clinical practice.
Sections du résumé
BACKGROUND AND AIM
OBJECTIVE
The inflammatory bowel disease [IBD]-disk is a 10-item self-questionnaire that is used to assess IBD-related disability. The aim of the present study was to evaluate this tool in the assessment of IBD daily-life burden.
METHODS
METHODS
A 1-week cross-sectional study was conducted in 42 centres affiliated in France and Belgium. Patients were asked to complete the IBD-disk [best score: 0, worst score: 100] and a visual analogue scale [VAS] of IBD daily-life burden [best score: 0, worst score: 10]. Analyses included internal consistency, correlation analysis, and diagnostic performance assessment.
RESULTS
RESULTS
Among the 2011 IBD outpatients who responded to the survey [67.8% of the patients had Crohn's disease], 49.9% were in clinical remission. The IBD-disk completion rate was 73.8%. The final analysis was conducted in this population [n = 1455 patients]. The mean IBD-disk score and IBD daily-life burden VAS were 39.0 ± 23.2 and 5.2 ± 2.9, respectively. The IBD-disk score was well correlated with the IBD daily-life burden VAS [r = 0.67; p <0.001]. At an optimal IBD-disk cut-off of 40, the area under the receiver operating characteristic curve [AUROC] for high IBD daily-life burden [VAS >5] was 0.81 (95% confidence interval [CI]: 0.79-0.83; p <0.001).
CONCLUSIONS
CONCLUSIONS
In a large cohort of patients, the IBD-disk score was well correlated with IBD daily-life burden, and it could be used in clinical practice.
Identifiants
pubmed: 33246337
pii: 6007776
doi: 10.1093/ecco-jcc/jjaa244
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
766-773Investigateurs
Aurelien Amiot
(A)
Sara Tadbiri
(S)
Charlotte Gagniere
(C)
Jenny Tannoury
(J)
Maria Nachury
(M)
Benjamin Pariente
(B)
Pauline Wils
(P)
Yoram Bouhnik
(Y)
Carmen Stefanescu
(C)
Xavier Treton
(X)
Melanie Serrero
(M)
Jerome Filippi
(J)
Xavier Hébuterne
(X)
Nadia Arab
(N)
Virginie Cluzeau
(V)
Xavier Roblin
(X)
Emilie Del Tedesco
(E)
Laurent Beaugerie
(L)
Philippe Seksik
(P)
Anne Bourrier
(A)
Cecilia Landmann
(C)
Julien Kirchgesner
(J)
Harry Sokol
(H)
Guillaume Bouguen
(G)
Laurent Siproudhis
(L)
Marie DeWit
(M)
Denis Franchimont
(D)
Guillaume Savoye
(G)
Anthony Buisson
(A)
Edouard Louis
(E)
Catherine Reenaers
(C)
Stephane Nancey
(S)
Gilles Boschetti
(G)
Claire Gay
(C)
Pauline Danion
(P)
Bernard Flourié
(B)
Vered Abitbol
(V)
Georgia Malamut
(G)
Jean-Marie Reimund
(JM)
Benedicte Caron
(B)
Olivier DeWit
(O)
Lucine Vuitton
(L)
Nicolas Mathieu
(N)
Sandie Pestour
(S)
Laurent Peyrin-Biroulet
(L)
Camille Zallot
(C)
Cyrielle Gilletta
(C)
Matthieu Allez
(M)
Jean-Marc Gornet
(JM)
Clotilde Baudry
(C)
Stephanie Viennot
(S)
Arnaud Bourreille
(A)
Caroline Trang-Poisson
(C)
Nina Dib
(N)
Hedi Brixi
(H)
Guillaume Cadiot
(G)
Medina Boualit
(M)
Claire Painchart
(C)
Laurianne Plastaras
(L)
Lucile Boivineau
(L)
Romain Altwegg
(R)
Mathurin Fumery
(M)
Ludovic Caillo
(L)
David Laharie
(D)
Pauline Riviere
(P)
Florian Poullenot
(F)
Benoit Coffin
(B)
Henri Duboc
(H)
Stephane Nahon
(S)
Noemie Tavernier
(N)
Marion Simon
(M)
Baya Coulibaly
(B)
Morgane Amil
(M)
Duveau Nicolas
(D)
Sherine Khater
(S)
Mehdi Kaassis
(M)
Felix Goutorbe
(F)
Driffa Moussata
(D)
Laurence Picon
(L)
Informations de copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of European Crohn’s and Colitis Organisation. All rights reserved. For permissions, please email: journals.permissions@oup.com.