Comparison of global end-diastolic volume index derived from jugular and femoral indicator injection: a prospective observational study in patients equipped with both a PiCCO-2 and an EV-1000-device.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
27 11 2020
Historique:
received: 19 09 2019
accepted: 28 02 2020
entrez: 28 11 2020
pubmed: 29 11 2020
medline: 10 4 2021
Statut: epublish

Résumé

Transpulmonary thermodilution (TPTD)-derived global end-diastolic volume index (GEDVI) is a static marker of preload which better predicted volume responsiveness compared to filling pressures in several studies. GEDVI can be generated with at least two devices: PiCCO and EV-1000. Several studies showed that uncorrected indicator injection into a femoral central venous catheter (CVC) results in a significant overestimation of GEDVI by the PiCCO-device. Therefore, the most recent PiCCO-algorithm corrects for femoral indicator injection. However, there are no systematic data on the impact of femoral indicator injection for the EV-1000 device. Furthermore, the correction algorithm of the PiCCO is poorly validated. Therefore, we prospectively analyzed 14 datasets from 10 patients with TPTD-monitoring undergoing central venous catheter (CVC)- and arterial line exchange. PiCCO was replaced by EV-1000, femoral CVCs were replaced by jugular/subclavian CVCs and vice-versa. For PiCCO, jugular and femoral indicator injection derived GEDVI was comparable when the correct information about femoral catheter site was given (p = 0.251). By contrast, GEDVI derived from femoral indicator injection using the EV-1000 was obviously not corrected and was substantially higher than jugular GEDVI measured by the EV-1000 (846 ± 250 vs. 712 ± 227 ml/m

Identifiants

pubmed: 33247165
doi: 10.1038/s41598-020-76286-w
pii: 10.1038/s41598-020-76286-w
pmc: PMC7695713
doi:

Substances chimiques

Indicators and Reagents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

20773

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Auteurs

Alexander Herner (A)

II. Medizinische Klinik Und Poliklinik, Klinikum Rechts Der Isar Der Technischen Universität München, Ismaninger Straße 22, 81675, Munich, Germany.

Markus Heilmaier (M)

II. Medizinische Klinik Und Poliklinik, Klinikum Rechts Der Isar Der Technischen Universität München, Ismaninger Straße 22, 81675, Munich, Germany.

Ulrich Mayr (U)

II. Medizinische Klinik Und Poliklinik, Klinikum Rechts Der Isar Der Technischen Universität München, Ismaninger Straße 22, 81675, Munich, Germany.

Roland M Schmid (RM)

II. Medizinische Klinik Und Poliklinik, Klinikum Rechts Der Isar Der Technischen Universität München, Ismaninger Straße 22, 81675, Munich, Germany.

Wolfgang Huber (W)

II. Medizinische Klinik Und Poliklinik, Klinikum Rechts Der Isar Der Technischen Universität München, Ismaninger Straße 22, 81675, Munich, Germany. Wolfgang.Huber@tum.de.

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