Flow Volume Loop and Regional Ventilation Assessment Using Phase-Resolved Functional Lung (PREFUL) MRI: Comparison With


Journal

Journal of magnetic resonance imaging : JMRI
ISSN: 1522-2586
Titre abrégé: J Magn Reson Imaging
Pays: United States
ID NLM: 9105850

Informations de publication

Date de publication:
04 2021
Historique:
revised: 09 11 2020
received: 17 08 2020
accepted: 12 11 2020
pubmed: 29 11 2020
medline: 15 5 2021
entrez: 28 11 2020
Statut: ppublish

Résumé

Regional flow volume loop ventilation-weighted noncontrast-enhanced proton lung MRI in free breathing has emerged as a novel technique for assessment of regional lung ventilation, but has yet not been validated with To compare regional ventilation and regional flow volume loops measured by noncontrast-enhanced ventilation-weighted phase-resolved functional lung MRI (PREFUL-MRI) with Retrospective study. Twenty patients with COPD, eight patients with CF, and six healthy volunteers. PREFUL and Coronal slices of PREFUL-MRI (free breathing) and The obtained parameters were compared using Wilcoxon tests, correlated using Spearman's correlation coefficient (r), and agreement between PREFUL and VDP measured by PREFUL and Combined RV and RFVL PREFUL defect maps likely increase sensitivity to mild airway obstruction with increased VDP values compared to 3 TECHNICAL EFFICACY STAGE: 2.

Sections du résumé

BACKGROUND
Regional flow volume loop ventilation-weighted noncontrast-enhanced proton lung MRI in free breathing has emerged as a novel technique for assessment of regional lung ventilation, but has yet not been validated with
PURPOSE
To compare regional ventilation and regional flow volume loops measured by noncontrast-enhanced ventilation-weighted phase-resolved functional lung MRI (PREFUL-MRI) with
STUDY TYPE
Retrospective study.
POPULATION
Twenty patients with COPD, eight patients with CF, and six healthy volunteers.
FIELD STRENGTH/SEQUENCE
PREFUL and
ASSESSMENT
Coronal slices of PREFUL-MRI (free breathing) and
STATISTICAL TESTS
The obtained parameters were compared using Wilcoxon tests, correlated using Spearman's correlation coefficient (r), and agreement between PREFUL and
RESULTS
VDP measured by PREFUL and
DATA CONCLUSION
Combined RV and RFVL PREFUL defect maps likely increase sensitivity to mild airway obstruction with increased VDP values compared to
LEVEL OF EVIDENCE
3 TECHNICAL EFFICACY STAGE: 2.

Identifiants

pubmed: 33247456
doi: 10.1002/jmri.27452
doi:

Substances chimiques

Xenon Isotopes 0
Xenon 3H3U766W84

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1092-1105

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2020 The Authors. Journal of Magnetic Resonance Imaging published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.

Références

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Auteurs

Till F Kaireit (TF)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

Agilo Kern (A)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

Andreas Voskrebenzev (A)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

Gesa H Pöhler (GH)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

Filip Klimes (F)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

Lea Behrendt (L)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

Marcel Gutberlet (M)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

Tawfik Moher-Alsady (T)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

Anna-Maria Dittrich (AM)

Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.
Department for Paediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.

Frank Wacker (F)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

Jens Hohlfeld (J)

Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.
Clinic of Pneumology, Hannover Medical School, Hannover, Germany.
Fraunhofer Institute for T oxicology and Experimental Medicine, Hannover, Germany.

Jens Vogel-Claussen (J)

Department for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Lung Research Center (DZL), Hannover, Germany.

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