Association Between Nitric Oxide, Oxidative Stress, Eryptosis, Red Blood Cell Microparticles, and Vascular Function in Sickle Cell Anemia.
TLR4
endothelial cells
eryptosis
red blood cell microparticles
sickle cell anemia
vascular dysfunction
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2020
2020
Historique:
received:
13
04
2020
accepted:
14
10
2020
entrez:
30
11
2020
pubmed:
1
12
2020
medline:
1
5
2021
Statut:
epublish
Résumé
Chronic hemolysis, enhanced oxidative stress, and decreased nitric oxide (NO) bioavailability promote vasculopathy in sickle cell anemia (SCA). Oxidative stress and NO are known to modulate eryptosis in healthy red blood cells (RBCs); however, their role in SCA eryptosis and their impact on the genesis of RBC-derived microparticles (RBC-MPs) remains poorly described. RBC-MPs could play a role in vascular dysfunction in SCA. The aims of this study were to evaluate the roles of oxidative stress and NO in eryptosis and RBC-MPs release, and to determine whether RBC-MPs could be involved in vascular dysfunction in SCA. Markers of eryptosis and oxidative stress, plasma RBC-MPs concentration and arterial stiffness were compared between SCA and healthy (AA) individuals
Identifiants
pubmed: 33250889
doi: 10.3389/fimmu.2020.551441
pmc: PMC7672038
doi:
Substances chimiques
Nitric Oxide
31C4KY9ESH
Types de publication
Clinical Trial
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
551441Informations de copyright
Copyright © 2020 Nader, Romana, Guillot, Fort, Stauffer, Lemonne, Garnier, Skinner, Etienne-Julan, Robert, Gauthier, Cannas, Antoine-Jonville, Tressières, Hardy-Dessources, Bertrand, Martin, Renoux, Joly, Grau and Connes.
Références
J Biol Chem. 2014 Apr 18;289(16):11512-21
pubmed: 24616094
Eur J Haematol. 2002 Jun;68(6):327-31
pubmed: 12225389
Circulation. 2016 Sep 27;134(13):923-33
pubmed: 27582423
Free Radic Res. 2013 May;47(5):357-67
pubmed: 23472882
Pflugers Arch. 2008 May;456(2):293-305
pubmed: 18058124
Front Physiol. 2017 Dec 12;8:977
pubmed: 29311949
Circ J. 2010 Jan;74(1):24-33
pubmed: 19920359
Blood. 2014 Jan 16;123(3):377-90
pubmed: 24277079
Clin Hemorheol Microcirc. 2018;68(2-3):319-329
pubmed: 29614639
Nitric Oxide. 2018 Dec 1;81:28-35
pubmed: 30342855
Nat Cell Biol. 2002 Oct;4(10):743-9
pubmed: 12244325
Nat Rev Dis Primers. 2018 Mar 15;4:18010
pubmed: 29542687
J Clin Hypertens (Greenwich). 2015 Sep;17(9):726-31
pubmed: 25991400
Br J Haematol. 2017 Mar;176(5):805-813
pubmed: 27984639
Clin Hemorheol Microcirc. 2009;42(2):75-97
pubmed: 19433882
Nat Med. 2002 Dec;8(12):1383-9
pubmed: 12426562
Blood. 2020 Jul 9;136(2):247-256
pubmed: 32285120
Cytokine. 2010 Jan;49(1):39-44
pubmed: 19900820
Methods Enzymol. 2008;441:295-315
pubmed: 18554541
Br J Haematol. 2018 Aug;182(3):444-448
pubmed: 28643376
Front Physiol. 2019 Aug 13;10:976
pubmed: 31456691
Blood. 2000 Aug 1;96(3):1119-24
pubmed: 10910931
Br J Haematol. 2017 Aug;178(3):468-475
pubmed: 28466542
J Lab Clin Med. 1994 May;123(5):741-8
pubmed: 8195679
Clin Hemorheol Microcirc. 2014;57(1):9-22
pubmed: 24002118
Anemia. 2011;2011:379894
pubmed: 21490763
PLoS One. 2013;8(2):e56759
pubmed: 23424675
Blood. 2002 Mar 1;99(5):1564-71
pubmed: 11861269
Blood Cells Mol Dis. 2011 Mar 15;46(3):220-5
pubmed: 21334230
J Extracell Vesicles. 2015 Nov 23;4:28414
pubmed: 26609806
Blood Cells Mol Dis. 2017 May;64:23-29
pubmed: 28340403
Clin Hemorheol Microcirc. 2018;68(2-3):105-128
pubmed: 29614627
Anal Biochem. 1979 Jun;95(2):351-8
pubmed: 36810
Semin Cell Dev Biol. 2015 Mar;39:35-42
pubmed: 25636585
Free Radic Biol Med. 2006 Aug 15;41(4):541-8
pubmed: 16863986
Front Physiol. 2017 Sep 06;8:673
pubmed: 28932200
Blood. 2013 Mar 14;121(11):2099-107
pubmed: 23349388
Am J Hematol. 2009 Sep;84(9):618-25
pubmed: 19610078
Blood Cells Mol Dis. 2016 Jul;59:134-9
pubmed: 27282583
Curr Opin Hematol. 2013 May;20(3):201-7
pubmed: 23519154
Clin Hemorheol Microcirc. 2016;62(2):173-9
pubmed: 26444610
Eur J Clin Invest. 2011 May;41(5):546-51
pubmed: 21158851
Cell Mol Life Sci. 2003 Jan;60(1):6-20
pubmed: 12613655
PLoS One. 2009 Nov 23;4(11):e7956
pubmed: 19956689
Clin Hemorheol Microcirc. 2018;68(2-3):165-172
pubmed: 29614630
Br J Haematol. 2009 Aug;146(4):447-55
pubmed: 19549270
Platelets. 2013;24(8):605-14
pubmed: 23249216
Blood Rev. 2007 Jan;21(1):37-47
pubmed: 17084951
Arterioscler Thromb Vasc Biol. 2002 Jan;22(1):147-52
pubmed: 11788475
Haematologica. 2009 Nov;94(11):1513-9
pubmed: 19815831
Pulse (Basel). 2017 Jan;4(4):180-192
pubmed: 28229053
Free Radic Biol Med. 2003 Oct 1;35(7):790-6
pubmed: 14583343
Ann Hematol. 2012 Jul;91(7):1097-105
pubmed: 22318468
Blood. 2015 Jun 11;125(24):3805-14
pubmed: 25827830
Kidney Int Suppl. 2003 May;(84):S11-4
pubmed: 12694298
Blood. 2015 Jun 11;125(24):3677-8
pubmed: 26069333
Blood. 2003 Jul 1;102(1):365-70
pubmed: 12609840
Am J Physiol Cell Physiol. 2006 Jan;290(1):C244-53
pubmed: 16338977
Blood Rev. 2016 Mar;30(2):111-8
pubmed: 26341565
Blood. 2016 Feb 18;127(7):801-9
pubmed: 26758915
J Thromb Thrombolysis. 2014;38(2):167-75
pubmed: 24254379
JCI Insight. 2018 Nov 2;3(21):
pubmed: 30385713
Biochemistry. 2001 Aug 7;40(31):9438-46
pubmed: 11478914
Redox Biol. 2015 Dec;6:226-239
pubmed: 26285072
Blood. 2012 Dec 13;120(25):5050-8
pubmed: 22976952
Haematologica. 2013 Jun;98(6):862-7
pubmed: 23403312
Diabetes Care. 2015 Nov;38(11):2120-7
pubmed: 26324331
Antioxid Redox Signal. 2014 Jul 1;21(1):138-53
pubmed: 24359125
J Clin Invest. 2017 Mar 1;127(3):750-760
pubmed: 28248201
Cell Mol Biol (Noisy-le-grand). 2004 Feb;50(1):95-105
pubmed: 15040433