Prolonged survival after multimodal therapy for pleural mesothelioma: Don't give up the follow-up. A case report.
Long survival
Mesothelioma
Recurrence
Trimodal therapy
Journal
Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
31
08
2020
revised:
06
11
2020
accepted:
07
11
2020
entrez:
30
11
2020
pubmed:
1
12
2020
medline:
1
12
2020
Statut:
epublish
Résumé
Malignant Pleural mesothelioma (MPM) is a rare disease which is associated with a poor prognosis. Front line chemotherapy represents the cornerstone in the management of MPM, and the place of radical surgery is controversial and reserve in early-stage disease. However prolonged survival (more than 24 months) can be observed in rare cases and only in the context of multimodal treatment including surgical management. We report the case of a patient suffering from an epithelial MPM with a 14-years progression-free survival after trimodal treatment including extrapleural pneumonectomy followed by chemotherapy and radiotherapy. This case illustrates that despite being an aggressive disease, multimodal management including radical surgery may allow a prolonged response in MPM but requires a whole-life surveillance.
Identifiants
pubmed: 33251003
doi: 10.1016/j.amsu.2020.11.034
pii: S2049-0801(20)30462-3
pmc: PMC7683176
doi:
Types de publication
Case Reports
Langues
eng
Pagination
442-444Informations de copyright
© 2020 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.
Déclaration de conflit d'intérêts
None.
Références
J Thorac Oncol. 2013 Feb;8(2):238-45
pubmed: 23247629
Chest. 1995 Oct;108(4):1122-8
pubmed: 7555126
Eur Respir J. 2010 Mar;35(3):479-95
pubmed: 19717482
Lancet. 2016 Apr 2;387(10026):1405-1414
pubmed: 26719230
J Clin Oncol. 2003 Jul 15;21(14):2636-44
pubmed: 12860938
J Clin Oncol. 2005 Oct 1;23(28):6881-9
pubmed: 16192580
Int J Surg. 2018 Dec;60:132-136
pubmed: 30342279
Lancet Oncol. 2011 Aug;12(8):763-72
pubmed: 21723781
BMJ Open Respir Res. 2018 Feb 14;5(1):e000266
pubmed: 29531746