Regulation of Gluconeogenesis by Aldo-keto-reductase 1a1b in Zebrafish.

Human Metabolism Molecular Genetics

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
18 Dec 2020
Historique:
received: 12 06 2020
revised: 08 10 2020
accepted: 30 10 2020
entrez: 30 11 2020
pubmed: 1 12 2020
medline: 1 12 2020
Statut: epublish

Résumé

Regulation of glucose homeostasis is a fundamental process to maintain blood glucose at a physiological level, and its dysregulation is associated with the development of several metabolic diseases. Here, we report on a zebrafish mutant for Aldo-keto-reductase 1a1b (

Identifiants

pubmed: 33251496
doi: 10.1016/j.isci.2020.101763
pii: S2589-0042(20)30960-3
pmc: PMC7683270
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101763

Informations de copyright

© 2020 The Authors.

Déclaration de conflit d'intérêts

The authors report no conflict of interest.

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Auteurs

Xiaogang Li (X)

Department of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany.

Felix Schmöhl (F)

Department of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany.

Haozhe Qi (H)

Department of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany.

Katrin Bennewitz (K)

Department of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany.

Christoph T Tabler (CT)

Department of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany.

Gernot Poschet (G)

Metabolomics Core Technology Platform, Centre for Organismal Studies, Heidelberg University, Heidelberg 69120, Germany.

Rüdiger Hell (R)

Metabolomics Core Technology Platform, Centre for Organismal Studies, Heidelberg University, Heidelberg 69120, Germany.

Nadine Volk (N)

Tissue Bank of the National Center for Tumor Diseases (NCT), Heidelberg 69120, Germany.

Tanja Poth (T)

CMCP - Center for Model System and Comparative Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg 69120, Germany.

Ingrid Hausser (I)

Electron Microscopy Lab, Institute of Pathology, University Hospital Heidelberg, Heidelberg 69120, Germany.

Jakob Morgenstern (J)

Department of Internal Medicine I and Clinical Chemistry, Heidelberg University Hospital, Heidelberg 69120, Germany.

Thomas Fleming (T)

Department of Internal Medicine I and Clinical Chemistry, Heidelberg University Hospital, Heidelberg 69120, Germany.

Peter Paul Nawroth (PP)

Department of Internal Medicine I and Clinical Chemistry, Heidelberg University Hospital, Heidelberg 69120, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg 85764, Germany.
Joint Heidelberg-IDC Translational Diabetes Program, Helmholtz-Zentrum, München, Heidelberg 69120, Germany.

Jens Kroll (J)

Department of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany.

Classifications MeSH