Doxorubicin-Conjugated Iron Oxide Nanoparticles Synthesized by Laser Pyrolysis: In Vitro Study on Human Breast Cancer Cells.

breast human cells doxorubicin drug delivery in vitro cytotoxicity iron oxide nanoparticles

Journal

Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357

Informations de publication

Date de publication:
26 Nov 2020
Historique:
received: 02 11 2020
revised: 22 11 2020
accepted: 24 11 2020
entrez: 1 12 2020
pubmed: 2 12 2020
medline: 2 12 2020
Statut: epublish

Résumé

Even today, breast cancer remains a global public problem, with a high mortality rate among women. Nanoparticle (NP) based systems are developed to enhance drug delivery, reducing the toxic effect of medicine molecules. By using iron oxide nanoparticles for cancer treatment, several advantages were highlighted: the ability to target specific locations derived from their magnetic properties and reduced side effects. The aim of this study was to examine on breast cancer cell line the anticancer potential of γ-Fe

Identifiants

pubmed: 33256060
pii: polym12122799
doi: 10.3390/polym12122799
pmc: PMC7760716
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Ministry of Education and Research and UEFISCDI
ID : Contract no. 63PCCDI/2018 (PN-III-P1-1.2-PCCDI-2017-072), and Nucleu Programme, ctr. no. 16N /08.02.2019.

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Auteurs

Iulia Ioana Lungu (II)

National Institute of Laser, Plasma and Radiation Physics, 409 Atomistilor Street, 077125 Magurele, Ilfov, Romania.
Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.

Simona Nistorescu (S)

National Institute of Laser, Plasma and Radiation Physics, 409 Atomistilor Street, 077125 Magurele, Ilfov, Romania.
Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, Romania.

Mădălina Andreea Badea (MA)

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, Romania.

Andreea-Mihaela Petre (AM)

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, Romania.

Ana-Maria Udrea (AM)

National Institute of Laser, Plasma and Radiation Physics, 409 Atomistilor Street, 077125 Magurele, Ilfov, Romania.
Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, Romania.

Ana-Maria Banici (AM)

National Institute of Laser, Plasma and Radiation Physics, 409 Atomistilor Street, 077125 Magurele, Ilfov, Romania.

Claudiu Fleacă (C)

National Institute of Laser, Plasma and Radiation Physics, 409 Atomistilor Street, 077125 Magurele, Ilfov, Romania.

Ecaterina Andronescu (E)

Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.

Anca Dinischiotu (A)

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, Romania.

Florian Dumitrache (F)

National Institute of Laser, Plasma and Radiation Physics, 409 Atomistilor Street, 077125 Magurele, Ilfov, Romania.

Angela Staicu (A)

National Institute of Laser, Plasma and Radiation Physics, 409 Atomistilor Street, 077125 Magurele, Ilfov, Romania.

Mihaela Balaș (M)

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, Romania.

Classifications MeSH