Redox-Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy.
Cys-sulfinylation/Cys-sulfonylation
glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
obstructive sleep apnea (OSA)
peroxiredoxin-2 (PRDX2)
positive airway pressure (PAP)
proteomics-biomarkers
Journal
Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981
Informations de publication
Date de publication:
26 Nov 2020
26 Nov 2020
Historique:
received:
31
10
2020
revised:
19
11
2020
accepted:
23
11
2020
entrez:
1
12
2020
pubmed:
2
12
2020
medline:
2
12
2020
Statut:
epublish
Résumé
In this study, we examined the effect of six months of positive airway pressure (PAP) therapy on Obstructive Sleep Apnea (OSA) red blood cell (RBC) proteome by two dimensional difference gel electrophoresis (2D-DIGE) - based proteomics followed by Western blotting (WB) validation. The discovered dysregulated proteins/proteoforms are associated with cell death, H
Identifiants
pubmed: 33256145
pii: antiox9121184
doi: 10.3390/antiox9121184
pmc: PMC7761104
pii:
doi:
Types de publication
Journal Article
Langues
eng
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