Impact of SARS-CoV-2 on multiple gestation pregnancy.
Acute respiratory distress syndrome
COVID-19
Multiple gestation pregnancy
SARS-CoV-2 infection
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
ISSN: 1879-3479
Titre abrégé: Int J Gynaecol Obstet
Pays: United States
ID NLM: 0210174
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
23
10
2020
revised:
06
11
2020
accepted:
27
11
2020
pubmed:
2
12
2020
medline:
3
2
2021
entrez:
1
12
2020
Statut:
ppublish
Résumé
To assess clinical presentations, pregnancy complications, and maternal and neonatal outcomes among women with multiple gestation pregnancy (MGP) and confirmed SARS-CoV-2 (COVID-19) infection and to compare the data with a pre-pandemic period. A retrospective study at a dedicated COVID-19 Hospital in Mumbai, India. Data were obtained from the PregCovid Registry of pregnant and postpartum women with PCR-confirmed SARS-CoV-2 infection from April to September, 2020. Data were also compared with a cohort of women with MGP attending the hospital pre-pandemic (n = 63). Data from 879 women (singleton pregnancy, n = 859; MGP, n = 20) with COVID-19 were assessed. The twinning rate was 34.2 per 1000 births. As compared with singleton pregnancies, a higher proportion of women with MGP and Covid-19 delivered preterm (P = 0.001). Spontaneous abortions were also higher in the MGP group than in the singleton group (P = 0.055). The incidence of pre-eclampsia/eclampsia was higher in the COVID-19 MGP group than in both the COVID-19 singleton (41.6% vs. 7.9%) and pre-pandemic MGP (50.0% vs. 12.7%) groups. There was a higher risk of pre-eclampsia among women with MGP and COVID-19. Women with MGP and COVID-19 infection should receive special attention with a multidisciplinary approach to both maternal and neonatal care during the pandemic.
Identifiants
pubmed: 33259652
doi: 10.1002/ijgo.13508
pmc: PMC7611278
mid: EMS130362
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
220-225Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : DBT-Wellcome Trust India Alliance
ID : IA/CPHI/18/1/503933
Pays : India
Informations de copyright
© 2020 International Federation of Gynecology and Obstetrics.
Références
BMJ. 2020 Jun 8;369:m2107
pubmed: 32513659
Asian J Psychiatr. 2020 Dec;54:102406
pubmed: 33271702
Int J Gynaecol Obstet. 2020 Nov;151(2):188-196
pubmed: 32757389
J Epidemiol Community Health. 1983 Jun;37(2):117-20
pubmed: 6886580
BMJ Open. 2019 Jul 4;9(7):e029908
pubmed: 31278106
BJOG. 2020 Oct;127(11):1374-1380
pubmed: 32479682
Eur J Obstet Gynecol Reprod Biol. 2021 Jan;256:503-505
pubmed: 33393481
Acta Genet Med Gemellol (Roma). 1997;46(1):47-56
pubmed: 9298158
PLoS One. 2011;6(9):e25239
pubmed: 21980404
Int J Gynaecol Obstet. 2020 Dec;151(3):459-462
pubmed: 33090458
BMJ. 2020 Jul 27;370:m2921
pubmed: 32718936