Hand dermatitis in adults referred for patch testing: Analysis of North American Contact Dermatitis Group Data, 2000 to 2016.
Adolescent
Adult
Aged
Aged, 80 and over
Allergens
/ adverse effects
Canada
/ epidemiology
Dermatitis, Allergic Contact
/ diagnosis
Dermatitis, Atopic
/ diagnosis
Dermatitis, Irritant
/ diagnosis
Dermatitis, Seborrheic
/ diagnosis
Eczema
/ diagnosis
Female
Hand Dermatoses
/ diagnosis
Humans
Irritants
/ adverse effects
Male
Metals
/ adverse effects
Middle Aged
Patch Tests
Preservatives, Pharmaceutical
/ adverse effects
United States
/ epidemiology
Young Adult
allergic contact dermatitis
arm
atopic dermatitis
contact allergy
eczema
foot
hand
irritant contact dermatitis
Journal
Journal of the American Academy of Dermatology
ISSN: 1097-6787
Titre abrégé: J Am Acad Dermatol
Pays: United States
ID NLM: 7907132
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
26
10
2020
revised:
16
11
2020
accepted:
19
11
2020
pubmed:
2
12
2020
medline:
26
8
2021
entrez:
1
12
2020
Statut:
ppublish
Résumé
Hand eczema (HE) is a heterogeneous and burdensome disorder. To characterize the clinical characteristics, etiologies and allergen relevance in adults with HE referred for patch testing. Retrospective analysis (2000-2016) of North American Contact Dermatitis Group data (n = 37,113). Overall, 10,034 patients had HE, with differences of overlap between allergic contact, irritant contact, and atopic dermatitis. Allergic contact HE fluctuated, whereas atopic HE steadily increased, and irritant HE decreased over time. HE was associated with higher proportions of positive patch tests (67.5% vs 63.8%; χ No data on HE phenotype. HE in adults was associated with higher proportions of positive patch tests, with a heterogeneous profile of allergens. Patch testing remains an important tool in the evaluation of patients with HE.
Sections du résumé
BACKGROUND
BACKGROUND
Hand eczema (HE) is a heterogeneous and burdensome disorder.
OBJECTIVE
OBJECTIVE
To characterize the clinical characteristics, etiologies and allergen relevance in adults with HE referred for patch testing.
METHODS
METHODS
Retrospective analysis (2000-2016) of North American Contact Dermatitis Group data (n = 37,113).
RESULTS
RESULTS
Overall, 10,034 patients had HE, with differences of overlap between allergic contact, irritant contact, and atopic dermatitis. Allergic contact HE fluctuated, whereas atopic HE steadily increased, and irritant HE decreased over time. HE was associated with higher proportions of positive patch tests (67.5% vs 63.8%; χ
LIMITATIONS
CONCLUSIONS
No data on HE phenotype.
CONCLUSION
CONCLUSIONS
HE in adults was associated with higher proportions of positive patch tests, with a heterogeneous profile of allergens. Patch testing remains an important tool in the evaluation of patients with HE.
Identifiants
pubmed: 33259878
pii: S0190-9622(20)33103-0
doi: 10.1016/j.jaad.2020.11.054
pii:
doi:
Substances chimiques
Allergens
0
Irritants
0
Metals
0
Preservatives, Pharmaceutical
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
989-999Informations de copyright
Copyright © 2020 American Academy of Dermatology, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest None disclosed.