Targeting Stereotactic Body Radiotherapy on Metabolic PET- and Immuno-PET-Positive Vertebral Metastases.
CEA
CTV
GTV
PET-CT
bispecific antibody
immuno-PET
radiation oncology
stereotactic ablative body radiotherapy (SABR)
stereotactic body radiation therapy (SBRT)
targeting
vertebral metastases
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
28 Nov 2020
28 Nov 2020
Historique:
received:
21
10
2020
revised:
18
11
2020
accepted:
23
11
2020
entrez:
2
12
2020
pubmed:
3
12
2020
medline:
3
12
2020
Statut:
epublish
Résumé
(1) Background: Stereotactic body radiotherapy (SBRT) for vertebral metastases (VM) allows the delivery of high radiation doses to tumors while sparing the spinal cord. We report a new approach to clinical target volume (CTV) delineation based on anti-carcinoembryonic antigen (CEA) positron emission tomography (pretargeted immuno-PET; "iPET") in patients with metastatic breast cancer (BC) or medullary thyroid cancer (MTC). (2) Methods: All patients underwent iPET, spine magnetic resonance imaging (MRI), and positron emission tomography-computed tomography (PET-CT) using
Identifiants
pubmed: 33260610
pii: biomedicines8120548
doi: 10.3390/biomedicines8120548
pmc: PMC7760481
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Agence Nationale de la Recherche
ID : ANR-11-EQPX-0004
Organisme : Agence Nationale de la Recherche
ID : ANR-11-LABX-0018-01
Organisme : Direction Générale de l'offre de Soins
ID : INCa-DGOS-Inserm_12558 (SIRIC ILIAD)
Organisme : Centre Hospitalier Universitaire de Nantes
ID : no grant number
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