Novel Production of Bovine Papillomavirus Pseudovirions in Tobacco Plants.
BPV
biopharming
pseudovirion
Journal
Pathogens (Basel, Switzerland)
ISSN: 2076-0817
Titre abrégé: Pathogens
Pays: Switzerland
ID NLM: 101596317
Informations de publication
Date de publication:
28 Nov 2020
28 Nov 2020
Historique:
received:
29
10
2020
revised:
22
11
2020
accepted:
22
11
2020
entrez:
2
12
2020
pubmed:
3
12
2020
medline:
3
12
2020
Statut:
epublish
Résumé
Vaccine efficacy requires the production of neutralising antibodies which offer protection against the native virus. The current gold standard for determining the presence of neutralising antibodies is the pseudovirion-based neutralisation assay (PBNA). PBNAs utilise pseudovirions (PsVs), structures which mimic native virus capsids, but contain non-viral nucleic material. PsVs are currently produced in expensive cell culture systems, which limits their production, yet plant expression systems may offer cheaper, safer alternatives. Our aim was to determine whether plants could be used for the production of functional PsVs of bovine papillomavirus 1 (BPV1), an important causative agent of economically damaging bovine papillomas in cattle and equine sarcoids in horses and wild equids. BPV1 capsid proteins, L1 and L2, and a self-replicating reporter plasmid were transiently expressed in
Identifiants
pubmed: 33260725
pii: pathogens9120996
doi: 10.3390/pathogens9120996
pmc: PMC7760623
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Poliomyelitis Research Foundation (PRF)
ID : N/a
Organisme : Council for Scientific and Industrial Research (CSIR)
ID : n/a
Références
Biophys J. 1991 Dec;60(6):1445-56
pubmed: 1663794
Planta. 2012 Oct;236(4):1305-13
pubmed: 22718313
Can Vet J. 2015 Jul;56(7):709-14
pubmed: 26130832
Biotechniques. 1997 Nov;23(5):912-8
pubmed: 9383559
J Virol. 2001 Nov;75(21):10493-7
pubmed: 11581419
Hum Vaccin Immunother. 2014;10(3):740-6
pubmed: 24384608
Virology. 1996 May 1;219(1):37-44
pubmed: 8623552
Virology. 1996 Sep 1;223(1):174-84
pubmed: 8806551
Methods Mol Biol. 2009;515:275-85
pubmed: 19378126
Transbound Emerg Dis. 2010 Jun;57(3):185-96
pubmed: 20113447
Plant Biotechnol J. 2012 May;10(4):410-21
pubmed: 22260326
Plant Biotechnol J. 2018 Feb;16(2):628-637
pubmed: 28733985
Virology. 2000 Dec 20;278(2):570-7
pubmed: 11118379
Clin Vaccine Immunol. 2008 Jan;15(1):172-5
pubmed: 17989337
Virol J. 2014 Dec 03;11:205
pubmed: 25465382
J Gen Virol. 2017 Feb;98(2):230-241
pubmed: 28284277
J Clin Microbiol. 2013 Jul;51(7):2167-71
pubmed: 23637294
J S Afr Vet Assoc. 2011 Jun;82(2):80-5
pubmed: 22135920
Pathogens. 2020 May 30;9(6):
pubmed: 32486181
Curr Pharm Des. 2013;19(31):5564-73
pubmed: 23394559
Virology. 2009 Oct 10;393(1):1-6
pubmed: 19729180
Virology. 2004 Apr 10;321(2):205-16
pubmed: 15051381
Sci Rep. 2016 Feb 08;6:20431
pubmed: 26853456
J Virol. 2019 Jun 14;93(13):
pubmed: 30996086
Plant Mol Biol Report. 2013;31:1529-1538
pubmed: 24415845
PLoS One. 2015 Mar 18;10(3):e0120797
pubmed: 25785935
Vet J. 2014 Mar;199(3):340-7
pubmed: 24456796
J Gen Virol. 2011 Oct;92(Pt 10):2437-2445
pubmed: 21715602
J Gen Virol. 1996 Jul;77 ( Pt 7):1577-83
pubmed: 8758002
Mol Ther Methods Clin Dev. 2017 Apr 19;5:165-179
pubmed: 28497074
Plant Biotechnol J. 2010 Jun;8(5):620-37
pubmed: 20233333
Virus Res. 1993 May;28(2):195-202
pubmed: 7686316
Genet Mol Biol. 2017 Jan-Mar;40(1):1-21
pubmed: 28212457
Sci Rep. 2018 Jun 21;8(1):9426
pubmed: 29930292
J Virol. 2005 Mar;79(5):2839-46
pubmed: 15709003
J Gen Virol. 2007 May;88(Pt 5):1460-1469
pubmed: 17412974
Clin Dermatol. 1997 Mar-Apr;15(2):275-83
pubmed: 9167911
PLoS One. 2018 Jun 18;13(6):e0198996
pubmed: 29912929
J Infect Dis. 2009 Jul 15;200(2):166-71
pubmed: 19519255
J Mol Biol. 1996 Jun 7;259(2):249-63
pubmed: 8656427
Expert Rev Vaccines. 2016 Jul;15(7):853-62
pubmed: 26901354
Virus Res. 2002 Nov;89(2):249-61
pubmed: 12445664
Sci Rep. 2018 Sep 6;8(1):13310
pubmed: 30190493
Virology. 1991 Sep;184(1):33-42
pubmed: 1651594
Lancet Oncol. 2016 Jan;17(1):67-77
pubmed: 26652797
J Gen Virol. 2013 Feb;94(Pt 2):403-408
pubmed: 23100367
Papillomavirus Res. 2017 Jun;3:85-90
pubmed: 28720462
EClinicalMedicine. 2020 May 25;23:100353
pubmed: 32639485
Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12180-4
pubmed: 1334560
FASEB J. 2005 Mar;19(3):440-2
pubmed: 15640280
PLoS One. 2013 Oct 04;8(10):e75677
pubmed: 24124504
Hum Vaccin. 2007 Jul-Aug;3(4):109-15
pubmed: 17611417
J S Afr Vet Assoc. 2011 Jun;82(2):97-106
pubmed: 22135923
Vaccine. 2018 Jan 2;36(1):98-106
pubmed: 29174109
Virology. 1998 Apr 10;243(2):482-91
pubmed: 9568045
Hum Vaccin. 2008 Nov-Dec;4(6):425-34
pubmed: 18948732
Res Vet Sci. 2012 Oct;93(2):553-9
pubmed: 22100244
Plant Biotechnol J. 2010 Jan;8(1):38-46
pubmed: 19929900
J Virol. 2010 Feb;84(3):1214-20
pubmed: 19906917
Vet Pathol. 2011 Nov;48(6):1176-9
pubmed: 21169593
Curr Opin Biotechnol. 2015 Apr;32:156-162
pubmed: 25562816
Comp Immunol Microbiol Infect Dis. 2013 Jul;36(4):343-52
pubmed: 23561290
Brief Funct Genomics. 2018 Sep 27;17(5):295-307
pubmed: 29982427
Virology. 2000 Jul 5;272(2):382-93
pubmed: 10873782
Virology. 2004 Aug 1;325(2):320-7
pubmed: 15246271
J Virol. 2004 Jan;78(2):751-7
pubmed: 14694107
Methods Mol Med. 2005;119:445-62
pubmed: 16350417
Vet Pathol. 2009 Jul;46(4):636-41
pubmed: 19276046
PLoS One. 2016 Aug 12;11(8):e0160995
pubmed: 27518899
Plant Methods. 2018 Aug 25;14:71
pubmed: 30159002
Transbound Emerg Dis. 2016 Feb;63(1):14-23
pubmed: 24661978