Risk factors for having diabetic retinopathy at first screening in persons with type 1 diabetes diagnosed under 18 years of age.
Journal
Eye (London, England)
ISSN: 1476-5454
Titre abrégé: Eye (Lond)
Pays: England
ID NLM: 8703986
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
received:
13
02
2020
accepted:
13
11
2020
revised:
02
11
2020
pubmed:
3
12
2020
medline:
26
10
2021
entrez:
2
12
2020
Statut:
ppublish
Résumé
To determine the risk factors for having diabetic retinopathy (DR) in children and young people (CYP) with type 1 diabetes (T1DM) at first screening. Records from the Diabetes Eye Screening Wales (DESW) service for people in Wales, UK, with T1DM diagnosed under age 18 years were combined with other electronic health record (EHR) data in the Secure Anonymised Information Linkage (SAIL) Databank. Data close to the screening date were collected, and risk factors derived from multivariate, multinomial logistic regression modelling. Data from 4172 persons, with median (lower quartile, upper quartile) age 16.3 (13.0, 22.3) years and duration of diabetes 6.6 (2.3, 12.3) years were analysed. 62.6% (n = 2613) had no DR, 26.7% (n = 1112) background DR, and 10.7% (n = 447) had referable DR (RDR). No RDR was observed under 19 years of age. Factors associated with an increased risk of DR were diabetes duration, elevated HbA This study found that 37.4% of the study cohort had DR at first screening, the risk being greater the longer the duration of diabetes or higher the HbA
Identifiants
pubmed: 33262478
doi: 10.1038/s41433-020-01326-8
pii: 10.1038/s41433-020-01326-8
pmc: PMC8452782
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2840-2847Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Informations de copyright
© 2020. The Author(s), under exclusive licence to Springer Nature Limited part of Springer Nature.
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