Moulds and
Journal
ERJ open research
ISSN: 2312-0541
Titre abrégé: ERJ Open Res
Pays: England
ID NLM: 101671641
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
10
05
2020
accepted:
04
09
2020
entrez:
2
12
2020
pubmed:
3
12
2020
medline:
3
12
2020
Statut:
epublish
Résumé
Sensitisation to moulds and We prospectively enrolled 56 CRS patients who underwent endoscopic sinus surgery (ESS) (20 with comorbid asthma) and 28 healthy controls between October 2015 and December 2017. CRS patients were followed up for 12 months after surgery. Type 2 inflammation-related biomarkers were analysed using blood, resected tissue samples and sputum. 10 allergens including Sensitisation rate to moulds and SEs in asthmatic patients was increased when changing the cut-off value of specific IgE titre from 0.35 UA·mL Mould/SE sensitisation (≥0.10 UA·mL
Sections du résumé
BACKGROUND
BACKGROUND
Sensitisation to moulds and
METHODS
METHODS
We prospectively enrolled 56 CRS patients who underwent endoscopic sinus surgery (ESS) (20 with comorbid asthma) and 28 healthy controls between October 2015 and December 2017. CRS patients were followed up for 12 months after surgery. Type 2 inflammation-related biomarkers were analysed using blood, resected tissue samples and sputum. 10 allergens including
RESULTS
RESULTS
Sensitisation rate to moulds and SEs in asthmatic patients was increased when changing the cut-off value of specific IgE titre from 0.35 UA·mL
CONCLUSION
CONCLUSIONS
Mould/SE sensitisation (≥0.10 UA·mL
Identifiants
pubmed: 33263034
doi: 10.1183/23120541.00265-2020
pii: 00265-2020
pmc: PMC7682667
pii:
doi:
Types de publication
Journal Article
Langues
eng
Informations de copyright
Copyright ©ERS 2020.
Déclaration de conflit d'intérêts
Conflict of interest: Y. Kanemitsu reports research grants from Novartis Pharma and Tanabe Mitsubishi Pharma for the submitted work, and grants from MSD and Kyowa-Kirin corporations outside the submitted work. Conflict of interest: K. Fukumitsu has received a grant from Novartis for 500 000 JPY and GSK for 2 000 000 JPY outside the submitted work. Conflict of interest: R. Kurokawa has nothing to disclose. Conflict of interest: N. Takeda has nothing to disclose. Conflict of interest: Y. Ozawa has nothing to disclose. Conflict of interest: A. Masaki has nothing to disclose. Conflict of interest: J. Ono is an employee of Shino-test corporation. Conflict of interest: K. Izuhara reports research grants from Shino-Test Corporation for the submitted work. Conflict of interest: J-M. Yap has nothing to disclose. Conflict of interest: H. Nishiyama has nothing to disclose. Conflict of interest: S. Fukuda reports speaker honoraria from AstraZeneca and Eli Lilly Japan outside the submitted work. Conflict of interest: T. Uemura has nothing to disclose. Conflict of interest: T. Tajiri has nothing to disclose. Conflict of interest: H Ohkubo has received a research grant from Boehringer Ingelheim outside the submitted work. Conflict of interest: K. Maeno reports speaker honoraria from Pfizer and Chugai Pharmaceutical outside the submitted work. Conflict of interest: Y. Ito has nothing to disclose. Conflict of interest: T. Oguri has received a research grant from Ono outside the submitted work. Conflict of interest: M. Takemura has received a research grant from Pfizer outside the submitted work. Conflict of interest: M. Suzuki reports a research grant from Kobayashi Foundation for the submitted work. Conflict of interest: A. Niimi reports personal fees from Astellas, AstraZeneca, Kyorin, GSK, MSD, Shionogi and Boehringer Ingelheim, and grants from Astellas outside the submitted work.
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