Validation of a composed COVID-19 chest radiography score: the CARE project.
Journal
ERJ open research
ISSN: 2312-0541
Titre abrégé: ERJ Open Res
Pays: England
ID NLM: 101671641
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
08
06
2020
accepted:
03
08
2020
entrez:
2
12
2020
pubmed:
3
12
2020
medline:
3
12
2020
Statut:
epublish
Résumé
The aim of this study was to validate a composed coronavirus disease 2019 (COVID-19) chest radiography score (CARE) based on the extension of ground-glass opacity (GG) and consolidations (Co), separately assessed, and to investigate its prognostic performance. COVID-19-positive patients referring to our tertiary centre during the first month of the outbreak in our area and with a known outcome were retrospectively evaluated. Each lung was subdivided into three areas and a three-grade score assessing the extension of GG and Co was used. The CARE was derived from the sum of the subscores. A mixed-model ANOVA with A total of 1203 chest radiographs of 175 patients (120 males; mean age 67.81±15.5 years old) were examined. On average, each patient underwent 6.8±10.3 radiographs. Patients in ICU as well as deceased patients showed higher CARE scores (p<0.05, each). Age, Co and CARE significantly influenced the outcome (p<0.05 each). The CARE demonstrated good accuracy (area under the curve (AUC)=0.736) using longitudinal data as well as at admission only (AUC=0.740). A CARE score of 17.5 during hospitalisation showed 75% sensitivity and 69.9% specificity. The CARE was demonstrated to be a reliable tool to assess the severity of pulmonary involvement at chest radiography with a good prognostic performance.
Identifiants
pubmed: 33263058
doi: 10.1183/23120541.00359-2020
pii: 00359-2020
pmc: PMC7682711
pii:
doi:
Types de publication
Journal Article
Langues
eng
Informations de copyright
Copyright ©ERS 2020.
Déclaration de conflit d'intérêts
Conflict of interest: C. Giraudo has nothing to disclose. Conflict of interest: A. Cavaliere has nothing to disclose. Conflict of interest: G. Fichera has nothing to disclose. Conflict of interest: M. Weber has nothing to disclose. Conflict of interest: R. Motta has nothing to disclose. Conflict of interest: M. Pelloso has nothing to disclose. Conflict of interest: F. Tosato has nothing to disclose. Conflict of interest: A. Lupi has nothing to disclose. Conflict of interest: F. Calabrese has nothing to disclose. Conflict of interest: G. Carretta has nothing to disclose. Conflict of interest: A.M. Cattelan has nothing to disclose. Conflict of interest: G. De Conti has nothing to disclose. Conflict of interest: V. Cianci has nothing to disclose. Conflict of interest: P. Navalesi has nothing to disclose. Conflict of interest: M. Plebani has nothing to disclose. Conflict of interest: F. Rea has nothing to disclose. Conflict of interest: R. Vettor has nothing to disclose. Conflict of interest: A. Vianello has nothing to disclose. Conflict of interest: R. Stramare has nothing to disclose.
Références
Br J Radiol. 2012 Jun;85(1014):729-35
pubmed: 22167502
J Assoc Physicians India. 2013 Sep;61(9):597-8
pubmed: 24772693
Radiol Med. 2020 May;125(5):514-516
pubmed: 32350796
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
Virchows Arch. 2020 Jun;476(6):821-823
pubmed: 32350596
J Thorac Imaging. 2020 Jul;35(4):W105-W106
pubmed: 32404797
Eur Rev Med Pharmacol Sci. 2020 Mar;24(6):3404-3410
pubmed: 32271459
Rev Port Pneumol. 2012 May-Jun;18(3):120-7
pubmed: 22483844
Radiology. 2020 Aug;296(2):E115-E117
pubmed: 32073353
Immunol Res. 2020 Jun;68(3):161-168
pubmed: 32524333
Indian J Radiol Imaging. 2017 Jul-Sep;27(3):342-349
pubmed: 29089687
Eur J Radiol. 2018 Oct;107:196-202
pubmed: 30292266
Radiol Med. 2020 May;125(5):509-513
pubmed: 32358689
Clin Chem Lab Med. 2020 Jun 25;58(7):1149-1151
pubmed: 32242829
Lancet Infect Dis. 2020 Apr;20(4):425-434
pubmed: 32105637
Radiol Med. 2020 May;125(5):461-464
pubmed: 32358691
Eur Radiol. 2020 Aug;30(8):4381-4389
pubmed: 32193638
Virchows Arch. 2020 Sep;477(3):359-372
pubmed: 32642842
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Radiology. 2008 Mar;246(3):697-722
pubmed: 18195376
Radiology. 2020 Aug;296(2):E41-E45
pubmed: 32049601
Radiology. 2020 Oct;297(1):E197-E206
pubmed: 32407255