Severe Keratitis and Corneal Perforation by Paenibacillus glucanolyticus.
Cornea
/ diagnostic imaging
Corneal Perforation
/ diagnosis
Eye Infections, Bacterial
/ microbiology
Gram-Positive Bacterial Infections
/ complications
Humans
Keratitis
/ complications
Male
Middle Aged
Paenibacillus
/ isolation & purification
Severity of Illness Index
Tomography, Optical Coherence
/ methods
Journal
Cornea
ISSN: 1536-4798
Titre abrégé: Cornea
Pays: United States
ID NLM: 8216186
Informations de publication
Date de publication:
01 Aug 2021
01 Aug 2021
Historique:
received:
12
08
2020
accepted:
12
09
2020
pubmed:
3
12
2020
medline:
15
12
2021
entrez:
2
12
2020
Statut:
ppublish
Résumé
To report the first case of Paenibacillus glucanolyticus, a spore-forming bacteria, to be isolated in a human ocular infection. We describe a severe case of noncontact lens-related microbial keratitis due to P. glucanolyticus presenting with a large corneal abscess, severe ocular inflammation, and a large epithelial defect. The corneal scrapes with no growth initially cultured P. glucanolyticus on blood agar after 48 hours, with sensitivity to gentamicin and fluoroquinolones. No other organism was cultured. The patient had severe keratitis with a protracted course requiring cyanoacrylate glue patching because of keratolysis and perforation. The patient may benefit from a penetrating keratoplasty and extracapsular cataract extraction in due course to aid visual rehabilitation. This is the first reported ocular case of P. glucanolyticus demonstrating its bacterial virulence and pathogenic potential when infecting the cornea. Rapid identification with newer technology enable us to accurately identify these opportunistic bacteria and may give a more favorable visual outcome as correct sensitivities lead to timely treatment administration.
Identifiants
pubmed: 33264149
pii: 00003226-202108000-00022
doi: 10.1097/ICO.0000000000002584
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1062-1064Informations de copyright
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The authors have no funding or conflicts of interest to disclose.
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