TET2 genetic predisposition myeloproliferative neoplasms single nucleotide polymorphisms

Journal

Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269

Informations de publication

Date de publication:
01 Dec 2020
Historique:
received: 23 10 2020
revised: 25 11 2020
accepted: 29 11 2020
entrez: 4 12 2020
pubmed: 5 12 2020
medline: 5 12 2020
Statut: epublish

Résumé

The complexity of myeloproliferative neoplasms (MPNs) cannot be characterized by acquired somatic mutations alone. Individual genetic background is thought to contribute to the development of MPNs. The aim of our study was to assess the association between the We evaluated the Significant association between The

Sections du résumé

BACKGROUND BACKGROUND
The complexity of myeloproliferative neoplasms (MPNs) cannot be characterized by acquired somatic mutations alone. Individual genetic background is thought to contribute to the development of MPNs. The aim of our study was to assess the association between the
METHODS METHODS
We evaluated the
RESULTS RESULTS
Significant association between
CONCLUSIONS CONCLUSIONS
The

Identifiants

pubmed: 33271790
pii: jpm10040259
doi: 10.3390/jpm10040259
pmc: PMC7711989
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Ministry of Research and Education, Romania
ID : PN-III-P1-1.1-PD-2016-1414

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Auteurs

Diana L Lighezan (DL)

Department of Hematology, "Victor Babeș" University of Medicine and Pharmacy, 2, Eftimie Murgu Square, 300041 Timișoara, Romania.

Anca S Bojan (AS)

Department of Hematology, The Oncology Institute "Ion Chiricuță", "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Mihaela Iancu (M)

Department of Medical Informatics and Biostatistics, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Raluca M Pop (RM)

Department of Pharmacology and Toxicology, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Ștefana Gligor-Popa (Ș)

Department of Genetics, The Oncology Institute "Ion Chiricuță", 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.

Florin Tripon (F)

Department of Medical Genetics, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 38, Gheorghe Marinescu Street, 540139 Târgu-Mureș, Romania.
Center for Advanced Medical and Pharmaceutical Research, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 38, Gheorghe Marinescu Street, 540139 Târgu-Mureș, Romania.

Adriana S Cosma (AS)

Department of Medical Genetics, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 38, Gheorghe Marinescu Street, 540139 Târgu-Mureș, Romania.
Center for Advanced Medical and Pharmaceutical Research, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 38, Gheorghe Marinescu Street, 540139 Târgu-Mureș, Romania.

Ciprian Tomuleasa (C)

Department of Hematology, The Oncology Institute "Ion Chiricuță", "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Delia Dima (D)

Department of Hematology, The Oncology Institute "Ion Chiricuță", "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Mihnea Zdrenghea (M)

Department of Hematology, The Oncology Institute "Ion Chiricuță", "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Bogdan Fetica (B)

Department of Pathology, The Oncology Institute "Ion Chiricuță", 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.

Ioana Ioniță (I)

Department of Hematology, "Victor Babeș" University of Medicine and Pharmacy, 2, Eftimie Murgu Square, 300041 Timișoara, Romania.

Ildikó O Gaál (IO)

Department of Medical Genetics, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Simona Vișan (S)

Department of Genetics, The Oncology Institute "Ion Chiricuță", 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.

Andreea-Manuela Mirea (AM)

Department of Medical Genetics, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Radu A Popp (RA)

Department of Medical Genetics, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Mira Florea (M)

Department of Community Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Cătălin Araniciu (C)

Department of Therapeutic Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Lucian Petrescu (L)

Department of Cardiology, "Victor Babeș" University of Medicine and Pharmacy, 2, Eftimie Murgu Square, 300041 Timișoara, Romania.

Ioan V Pop (IV)

Department of Medical Genetics, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Claudia Bănescu (C)

Department of Medical Genetics, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 38, Gheorghe Marinescu Street, 540139 Târgu-Mureș, Romania.
Center for Advanced Medical and Pharmaceutical Research, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 38, Gheorghe Marinescu Street, 540139 Târgu-Mureș, Romania.

Adrian P Trifa (AP)

Department of Genetics, The Oncology Institute "Ion Chiricuță", 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.
Center for Advanced Medical and Pharmaceutical Research, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 38, Gheorghe Marinescu Street, 540139 Târgu-Mureș, Romania.
Department of Medical Genetics, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Classifications MeSH