Expectant Management of a Critically Ill Pregnant Patient with COVID-19 with Good Maternal and Neonatal Outcomes.


Journal

Case reports in obstetrics and gynecology
ISSN: 2090-6684
Titre abrégé: Case Rep Obstet Gynecol
Pays: United States
ID NLM: 101576454

Informations de publication

Date de publication:
2020
Historique:
received: 06 08 2020
revised: 04 11 2020
accepted: 16 11 2020
entrez: 4 12 2020
pubmed: 5 12 2020
medline: 5 12 2020
Statut: epublish

Résumé

Coronavirus Disease 2019 (COVID-19) is responsible for a global pandemic that has significantly affected New York City. There is limited data about COVID-19 infection in pregnancy, especially in critically ill patients. A 30-year-old female who presented at 26 weeks gestation with acute severe respiratory distress that required intubation and intensive care unit (ICU) admission. We had a high suspicion of COVID-19 disease despite repeated negative SARS-CoV-2 PCR testing, with eventual positive COVID IgG antibody testing. Through an integration of obstetrical knowledge, critical care, and comparing outcomes from similar cases in the literature, we decided to expectantly manage her pregnancy and did not recommend administration of antenatal steroids. She was extubated after 23 days of mechanical ventilation and recovered from her respiratory illness. She had a full-term spontaneous vaginal delivery of a baby boy at 39 weeks gestation with excellent maternal and fetal outcomes at delivery. In the face of COVID-19, a new disease with unclear maternal and fetal outcomes to date, a collaboration of care teams is essential to navigate through the challenging decisions made, including timing of delivery, treatment options, and administration of steroids. Our paper is unique as there is no other published case report of a critically ill pregnant patient with COVID-19 in which delivery was deferred, and a full recovery was observed, with a vaginal delivery at term.

Sections du résumé

BACKGROUND BACKGROUND
Coronavirus Disease 2019 (COVID-19) is responsible for a global pandemic that has significantly affected New York City. There is limited data about COVID-19 infection in pregnancy, especially in critically ill patients.
CASE METHODS
A 30-year-old female who presented at 26 weeks gestation with acute severe respiratory distress that required intubation and intensive care unit (ICU) admission. We had a high suspicion of COVID-19 disease despite repeated negative SARS-CoV-2 PCR testing, with eventual positive COVID IgG antibody testing. Through an integration of obstetrical knowledge, critical care, and comparing outcomes from similar cases in the literature, we decided to expectantly manage her pregnancy and did not recommend administration of antenatal steroids. She was extubated after 23 days of mechanical ventilation and recovered from her respiratory illness. She had a full-term spontaneous vaginal delivery of a baby boy at 39 weeks gestation with excellent maternal and fetal outcomes at delivery.
CONCLUSION CONCLUSIONS
In the face of COVID-19, a new disease with unclear maternal and fetal outcomes to date, a collaboration of care teams is essential to navigate through the challenging decisions made, including timing of delivery, treatment options, and administration of steroids. Our paper is unique as there is no other published case report of a critically ill pregnant patient with COVID-19 in which delivery was deferred, and a full recovery was observed, with a vaginal delivery at term.

Identifiants

pubmed: 33274091
doi: 10.1155/2020/8891787
pmc: PMC7695992
doi:

Types de publication

Case Reports

Langues

eng

Pagination

8891787

Informations de copyright

Copyright © 2020 Farah Alsayyed et al.

Déclaration de conflit d'intérêts

The authors declares that they have no conflicts of interest.

Références

IDCases. 2020 May 05;20:e00791
pubmed: 32377507
Obstet Gynecol. 2007 Mar;109(3):669-77
pubmed: 17329519
Am J Perinatol. 2020 Jun;37(8):809-812
pubmed: 32274772
Pediatr Dev Pathol. 2020 May-Jun;23(3):177-180
pubmed: 32397896
Am J Obstet Gynecol. 2020 Aug;223(2):286-290
pubmed: 32371056
AJP Rep. 2020 Apr;10(2):e169-e175
pubmed: 32509416
Scand J Clin Lab Invest. 2020 Nov;80(7):536-540
pubmed: 32804580
Chin Med J (Engl). 2020 May 5;133(9):1087-1095
pubmed: 32358325
Am J Obstet Gynecol. 2020 Jul;223(1):109.e1-109.e16
pubmed: 32360108
Radiology. 2020 Aug;296(2):E32-E40
pubmed: 32101510
Nat Med. 2020 Jun;26(6):845-848
pubmed: 32350462
BMJ. 2020 Jun 8;369:m2107
pubmed: 32513659
Br J Clin Pharmacol. 2016 May;81(5):835-48
pubmed: 26700396
Arthritis Rheum. 2002 Apr;46(4):1123-4
pubmed: 11953993
Lancet. 2020 Feb 15;395(10223):473-475
pubmed: 32043983
Respir Res. 2020 Jul 3;21(1):169
pubmed: 32620118
Obstet Gynecol. 2019 May;133(5):e303-e319
pubmed: 31022122
N Engl J Med. 2020 Nov 5;383(19):1813-1826
pubmed: 32445440
Int J Antimicrob Agents. 2020 Jul;56(1):105949
pubmed: 32205204
Am J Obstet Gynecol MFM. 2020 Aug;2(3):100134
pubmed: 32391519
Am J Obstet Gynecol MFM. 2020 Aug;2(3):100130
pubmed: 32346672
Clin Chest Med. 2011 Mar;32(1):1-13
pubmed: 21277444

Auteurs

Farah Alsayyed (F)

Division of Obstetrics and Gynecology, New York Presbyterian-Brooklyn Methodist Hospital, Brooklyn, NY, USA.

Victoria Hastings (V)

Division of Obstetrics and Gynecology, New York Presbyterian-Brooklyn Methodist Hospital, Brooklyn, NY, USA.

Sanford Lederman (S)

Division of Obstetrics and Gynecology, New York Presbyterian-Brooklyn Methodist Hospital, Brooklyn, NY, USA.

Classifications MeSH