Development of a common scale for measuring healthy ageing across the world: results from the ATHLOS consortium.
Healthy ageing
data integration
functional ability
intrinsic capacity
item response theory
scale
Journal
International journal of epidemiology
ISSN: 1464-3685
Titre abrégé: Int J Epidemiol
Pays: England
ID NLM: 7802871
Informations de publication
Date de publication:
09 07 2021
09 07 2021
Historique:
accepted:
23
10
2020
pubmed:
5
12
2020
medline:
31
7
2021
entrez:
4
12
2020
Statut:
ppublish
Résumé
Research efforts to measure the concept of healthy ageing have been diverse and limited to specific populations. This diversity limits the potential to compare healthy ageing across countries and/or populations. In this study, we developed a novel measurement scale of healthy ageing using worldwide cohorts. In the Ageing Trajectories of Health-Longitudinal Opportunities and Synergies (ATHLOS) project, data from 16 international cohorts were harmonized. Using ATHLOS data, an item response theory (IRT) model was used to develop a scale with 41 items related to health and functioning. Measurement heterogeneity due to intra-dataset specificities was detected, applying differential item functioning via a logistic regression framework. The model accounted for specificities in model parameters by introducing cohort-specific parameters that rescaled scores to the main scale, using an equating procedure. Final scores were estimated for all individuals and converted to T-scores with a mean of 50 and a standard deviation of 10. A common scale was created for 343 915 individuals above 18 years of age from 16 studies. The scale showed solid evidence of concurrent validity regarding various sociodemographic, life and health factors, and convergent validity with healthy life expectancy (r = 0.81) and gross domestic product (r = 0.58). Survival curves showed that the scale could also be predictive of mortality. The ATHLOS scale, due to its reliability and global representativeness, has the potential to contribute to worldwide research on healthy ageing.
Sections du résumé
BACKGROUND
Research efforts to measure the concept of healthy ageing have been diverse and limited to specific populations. This diversity limits the potential to compare healthy ageing across countries and/or populations. In this study, we developed a novel measurement scale of healthy ageing using worldwide cohorts.
METHODS
In the Ageing Trajectories of Health-Longitudinal Opportunities and Synergies (ATHLOS) project, data from 16 international cohorts were harmonized. Using ATHLOS data, an item response theory (IRT) model was used to develop a scale with 41 items related to health and functioning. Measurement heterogeneity due to intra-dataset specificities was detected, applying differential item functioning via a logistic regression framework. The model accounted for specificities in model parameters by introducing cohort-specific parameters that rescaled scores to the main scale, using an equating procedure. Final scores were estimated for all individuals and converted to T-scores with a mean of 50 and a standard deviation of 10.
RESULTS
A common scale was created for 343 915 individuals above 18 years of age from 16 studies. The scale showed solid evidence of concurrent validity regarding various sociodemographic, life and health factors, and convergent validity with healthy life expectancy (r = 0.81) and gross domestic product (r = 0.58). Survival curves showed that the scale could also be predictive of mortality.
CONCLUSIONS
The ATHLOS scale, due to its reliability and global representativeness, has the potential to contribute to worldwide research on healthy ageing.
Identifiants
pubmed: 33274372
pii: 6020095
doi: 10.1093/ije/dyaa236
pmc: PMC8271194
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
880-892Subventions
Organisme : World Health Organization
ID : 001
Pays : International
Organisme : NIA NIH HHS
ID : R01 AG018016
Pays : United States
Informations de copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of the International Epidemiological Association.
Références
J Am Geriatr Soc. 2013 May;61 Suppl 2:S265-8
pubmed: 23662718
Int J Epidemiol. 2019 Feb 1;48(1):14-14j
pubmed: 30508091
Rev Esp Cardiol. 2011 Oct;64(10):876-82
pubmed: 21821340
BMJ Open. 2019 Nov 2;9(11):e026119
pubmed: 31678933
Int J Epidemiol. 2011 Oct;40(5):1314-28
pubmed: 21804097
Nutrients. 2018 Oct 30;10(11):
pubmed: 30380734
Int J Epidemiol. 2019 Aug 1;48(4):1052-1053i
pubmed: 31329885
Int J Epidemiol. 2013 Aug;42(4):992-1001
pubmed: 23778574
J Am Med Dir Assoc. 2017 Jun 1;18(6):460-464
pubmed: 28479271
Int J Epidemiol. 2013 Dec;42(6):1640-8
pubmed: 23143611
Clin Psychol Psychother. 2014 May-Jun;21(3):193-8
pubmed: 23881690
Gerontologist. 2019 Jul 16;59(4):e294-e310
pubmed: 29897451
J Gerontol A Biol Sci Med Sci. 2018 Nov 10;73(12):1653-1660
pubmed: 29408961
Int Psychogeriatr. 2014 Mar;26(3):373-81
pubmed: 24308764
Sci Rep. 2019 Jul 30;9(1):11041
pubmed: 31363117
Lancet. 2016 May 21;387(10033):2145-2154
pubmed: 26520231
Aging Clin Exp Res. 2019 Dec;31(12):1719-1725
pubmed: 31463926
Lancet. 2005 Mar 19-25;365(9464):1099-104
pubmed: 15781105
Int J Epidemiol. 2016 Aug;45(4):1054-1063
pubmed: 25468824
Psychol Methods. 2009 Jun;14(2):150-64
pubmed: 19485626
Biom J. 2020 Jan;62(1):34-52
pubmed: 31583767
Med Care. 2000 Sep;38(9 Suppl):II28-42
pubmed: 10982088
Int J Epidemiol. 2017 Feb 1;46(1):103-105
pubmed: 27272186
Int J Epidemiol. 2017 Apr 1;46(2):406-406i
pubmed: 27154633
Int J Epidemiol. 2017 Apr 1;46(2):e2
pubmed: 25626437
Sci Rep. 2017 Mar 10;7:43955
pubmed: 28281663
J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1512-1518
pubmed: 29346518
Int J Epidemiol. 2012 Dec;41(6):1639-49
pubmed: 23283715
BMC Public Health. 2006 Oct 18;6:255
pubmed: 17049075
Dev Psychol. 2008 Mar;44(2):365-80
pubmed: 18331129
Psychol Methods. 2009 Jun;14(2):81-100
pubmed: 19485623
Int J Epidemiol. 2014 Apr;43(2):576-85
pubmed: 24671021
Disabil Rehabil. 2017 Nov;39(23):2347-2380
pubmed: 27820966
Int J Epidemiol. 2014 Feb;43(1):61-8
pubmed: 23243115