Changes in Hippocampal Androgen Receptor Density and Behavior in Sprague-Dawley Male Rats Exposed to a Low-Pressure Blast Wave.
Testosterone
mTBI
military
neurotrauma
stress
Journal
Brain plasticity (Amsterdam, Netherlands)
ISSN: 2213-6312
Titre abrégé: Brain Plast
Pays: Netherlands
ID NLM: 101669568
Informations de publication
Date de publication:
01 Oct 2020
01 Oct 2020
Historique:
entrez:
7
12
2020
pubmed:
8
12
2020
medline:
8
12
2020
Statut:
epublish
Résumé
The purpose of this study was to examine the effect of exposure of a low-intensity blast wave on androgen receptor (AR) density in the hippocampus and the potential influence on behavioral and cognitive responses. Sprague-Dawley rats were randomly assigned to either a blast exposed group ( A significant elevation in anxiety index ( The results of this study demonstrate that exposure to a low-pressure blast wave resulted in a decrease in AR density, which was associated with significant behavioral and cognitive changes.
Identifiants
pubmed: 33282677
doi: 10.3233/BPL-200107
pii: BPL200107
pmc: PMC7685673
doi:
Types de publication
Journal Article
Langues
eng
Pagination
135-145Informations de copyright
© 2020 – IOS Press and the authors. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.
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