Radiotherapy for Head and Neck Cancer: Evaluation of Triggered Adaptive Replanning in Routine Practice.
adaptive radiotherapy
chemoradiotherapy (CRT)
head and neck cancer
replanning
volumetric modulated arc therapy (VMAT)
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2020
2020
Historique:
received:
03
07
2020
accepted:
13
10
2020
entrez:
7
12
2020
pubmed:
8
12
2020
medline:
8
12
2020
Statut:
epublish
Résumé
A proportion of patients receiving radiotherapy for head and neck squamous cell carcinoma (HNSCC) require A single center evaluation of all patients receiving radical or adjuvant (chemo)radiotherapy (CRT) for HNSCC between January and December 2016 was undertaken. Patients who underwent 31/290 (10.6%) HNSCC patients who underwent radical/adjuvant radiotherapy required re-planning. The adaptive radiotherapy (ART) was performed at a mean fraction of 15. The most common documented reasons for re-planning were tumor shrinkage (35.5%) and weight loss (35.5%). Among the patient/tumor/treatment factors, nasopharyngeal primary site (p = 0.013) and use of concurrent chemotherapy with radiotherapy (p = 0.034) were found to be significantly correlated with the need for re-planning. Effective on-treatment verification schedules and close follow up of patients especially with NPC primary and/or treated with concurrent chemoradiotherapy are crucial to identify patients requiring ART. We suggest an individualized triggered approach to ART rather than scheduled strategies as it is likely to be more feasible in terms of utilization of workload and resources.
Identifiants
pubmed: 33282734
doi: 10.3389/fonc.2020.579917
pmc: PMC7690320
doi:
Types de publication
Journal Article
Langues
eng
Pagination
579917Informations de copyright
Copyright © 2020 Figen, Çolpan Öksüz, Duman, Prestwich, Dyker, Cardale, Ramasamy, Murray and Şen.
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