Interobserver reliability of methods to determine complete resection of adenomas in colonoscopy.


Journal

Endoscopy
ISSN: 1438-8812
Titre abrégé: Endoscopy
Pays: Germany
ID NLM: 0215166

Informations de publication

Date de publication:
12 2021
Historique:
aheadofprint: 07 12 2020
pubmed: 8 12 2020
medline: 15 12 2021
entrez: 7 12 2020
Statut: ppublish

Résumé

Forceps margin biopsy and polypectomy specimen margins have both been used to assess for polypectomy resection adequacy. The interobserver reliability of the two methods has not been well described. The interpretability of polypectomy specimens for presence of residual neoplasia at the margin was assessed by two blinded pathologists. Next, the concordance of forceps margin biopsy interpretations between three blinded pathologists was evaluated by calculation of interobserver Rates of polypectomy specimen margin interpretability were low: 24/92 (26 %) for pathologist A, 28/92 (30.4 %) for pathologist B. Concordance of forceps margin biopsy interpretations (n = 129) between pathologists was high. Two internal pathologists showed substantial agreement in margin biopsy interpretations ( The majority of polypectomy specimen margins were uninterpretable by pathologists for presence of residual neoplasia. Forceps margin biopsy shows strong interobserver reliability in adenomatous lesions.

Sections du résumé

BACKGROUND
Forceps margin biopsy and polypectomy specimen margins have both been used to assess for polypectomy resection adequacy. The interobserver reliability of the two methods has not been well described.
METHODS
The interpretability of polypectomy specimens for presence of residual neoplasia at the margin was assessed by two blinded pathologists. Next, the concordance of forceps margin biopsy interpretations between three blinded pathologists was evaluated by calculation of interobserver
RESULTS
Rates of polypectomy specimen margin interpretability were low: 24/92 (26 %) for pathologist A, 28/92 (30.4 %) for pathologist B. Concordance of forceps margin biopsy interpretations (n = 129) between pathologists was high. Two internal pathologists showed substantial agreement in margin biopsy interpretations (
CONCLUSION
The majority of polypectomy specimen margins were uninterpretable by pathologists for presence of residual neoplasia. Forceps margin biopsy shows strong interobserver reliability in adenomatous lesions.

Identifiants

pubmed: 33285582
doi: 10.1055/a-1331-4446
doi:

Banques de données

ClinicalTrials.gov
['NCT03567863']

Types de publication

Clinical Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

1250-1255

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

Dr. Joshua Melson serves on the medical advisory board for Virgo Imaging. He has received grant funding from Boston Scientific. The remaining authors have no conflict of interest to disclose.

Auteurs

Erica Park (E)

Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.

William Barge (W)

Division of Gastroenterology and Hepatology, University of Wisconsin, Madison, Wisconsin, USA.

Jason Kramer (J)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Bana Alajati (B)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Shriram Jakate (S)

Department of Pathology, Rush University Medical Center, Chicago, Illinois, USA.

David Cimbaluk (D)

Department of Pathology, Rush University Medical Center, Chicago, Illinois, USA.

Deborah Giusto (D)

4Path Pathology Services Laboratory, Burr Ridge, Illinois, USA.

Ethan Ritz (E)

Clinical Informatics and Biostatistics, Rush University Medical Center, Chicago, Illinois, USA.

Faraz Bishehsari (F)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Saline Lee (S)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Shubha Singh (S)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

John Losurdo (J)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Michael Brown (M)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Mark DeMeo (M)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Rana Abraham (R)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Karen Ma (K)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Joshua Melson (J)

Division of Digestive Diseases and Nutrition, Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

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