Effectiveness of continuous monitoring by activity tracker of patients undergoing chemotherapy for urothelial carcinoma.


Journal

Cancer treatment and research communications
ISSN: 2468-2942
Titre abrégé: Cancer Treat Res Commun
Pays: England
ID NLM: 101694651

Informations de publication

Date de publication:
2020
Historique:
received: 29 09 2020
revised: 12 11 2020
accepted: 15 11 2020
pubmed: 9 12 2020
medline: 20 11 2021
entrez: 8 12 2020
Statut: ppublish

Résumé

It is difficult to objectively evaluate chemotherapy-related adverse events early in elderly patients with urothelial carcinoma. A delayed response causes a reduction in quality of life (QoL). Wearable activity systems that objectively record life logs have recently been used. This study was undertaken to verify the reliability and effectiveness of a wearable activity system (Fitbit) to monitor subjective symptoms in an objective manner during chemotherapy for elderly patients with urothelial cancer (UC). This was a cohort prospective study. Elderly patients with UC were enrolled who received short hydration gemcitabine and cisplatin (shGC) combination therapy at Nagoya City University Hospital from January 2018 to March 2020. A Fitbit was used to monitor heart rate, distance moved, and cardio zone time. Heart rate was also monitored by an oscillometric method. The relationship between Fitbit recordings and perceived adverse events, such as fatigue, constipation and nausea, observed during chemotherapy was investigated using a general linear mixed effects model. Twenty-one of 28 inpatients were enrolled and observed for a total of 824 days. A significant, moderately strong correlation was found between two measurements of heart rate (Pearson's r = 0.65, p < 0.05). The measurement of fatigue using Fitbit was effective (p = 0.03). Fitbit monitoring can measure the QoL of a patient and was useful for monitoring elderly patients with UC undergoing shGC therapy in an outpatient setting. Fitbit may be useful for monitoring outpatients and their QoL during chemotherapy.

Sections du résumé

BACKGROUND
It is difficult to objectively evaluate chemotherapy-related adverse events early in elderly patients with urothelial carcinoma. A delayed response causes a reduction in quality of life (QoL). Wearable activity systems that objectively record life logs have recently been used.
OBJECTIVES
This study was undertaken to verify the reliability and effectiveness of a wearable activity system (Fitbit) to monitor subjective symptoms in an objective manner during chemotherapy for elderly patients with urothelial cancer (UC).
MATERIALS AND METHODS
This was a cohort prospective study. Elderly patients with UC were enrolled who received short hydration gemcitabine and cisplatin (shGC) combination therapy at Nagoya City University Hospital from January 2018 to March 2020. A Fitbit was used to monitor heart rate, distance moved, and cardio zone time. Heart rate was also monitored by an oscillometric method. The relationship between Fitbit recordings and perceived adverse events, such as fatigue, constipation and nausea, observed during chemotherapy was investigated using a general linear mixed effects model.
RESULTS
Twenty-one of 28 inpatients were enrolled and observed for a total of 824 days. A significant, moderately strong correlation was found between two measurements of heart rate (Pearson's r = 0.65, p < 0.05). The measurement of fatigue using Fitbit was effective (p = 0.03).
CONCLUSION
Fitbit monitoring can measure the QoL of a patient and was useful for monitoring elderly patients with UC undergoing shGC therapy in an outpatient setting. Fitbit may be useful for monitoring outpatients and their QoL during chemotherapy.

Identifiants

pubmed: 33291048
pii: S2468-2942(20)30080-0
doi: 10.1016/j.ctarc.2020.100245
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

100245

Informations de copyright

Copyright © 2020. Published by Elsevier Ltd.

Auteurs

Yosuke Sugiyama (Y)

Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan; Department of Clinical Pharmaceutics, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.

Taku Naiki (T)

Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciencesy, Nagoya, Japan.

Yoshihiko Tasaki (Y)

Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan; Department of Clinical Pharmaceutics, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.

Tomoya Kataoka (T)

Department of Clinical Pharmaceutics, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.

Yoshihisa Mimura (Y)

Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan.

Yuki Kondo (Y)

Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan.

Toshiki Etani (T)

Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciencesy, Nagoya, Japan.

Keitaro Iida (K)

Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciencesy, Nagoya, Japan.

Satoshi Nozaki (S)

Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciencesy, Nagoya, Japan.

Ryosuke Ando (R)

Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciencesy, Nagoya, Japan.

Satoshi Osaga (S)

Clinical Research Management Center, Nagoya City University Hospital, Nagoya, Japan.

Takahiro Yasui (T)

Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciencesy, Nagoya, Japan.

Kazunori Kimura (K)

Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan; Department of Clinical Pharmaceutics, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan. Electronic address: kkimura@med.nagoya-cu.ac.jp.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH