Adiponectin Role in Neurodegenerative Diseases: Focus on Nutrition Review.
Adiponectin
Alzheimer’s disease
Parkinson’s disease
gut microbiota
gut-brain axis
healthy nutrition
neurodegenerative diseases
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
04 Dec 2020
04 Dec 2020
Historique:
received:
09
11
2020
revised:
30
11
2020
accepted:
02
12
2020
entrez:
9
12
2020
pubmed:
10
12
2020
medline:
9
3
2021
Statut:
epublish
Résumé
Adiponectin is an adipokine produced by adipose tissue. It has numerous beneficial effects. In particular, it improves metabolic effects and glucose homeostasis, lipid profile, and is involved in the regulation of cytokine profile and immune cell production, having anti-inflammatory and immune-regulatory effects. Adiponectin's role is already known in immune diseases and also in neurodegenerative diseases. Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are a set of diseases of the central nervous system, characterized by a chronic and selective process of neuron cell death, which occurs mainly in relation to oxidative stress and neuroinflammation. Lifestyle is able to influence the development of these diseases. In particular, unhealthy nutrition on gut microbiota, influences its composition and predisposition to develop many diseases such as neurodegenerative diseases, given the importance of the "gut-brain" axis. There is a strong interplay between Adiponectin, gut microbiota, and brain-gut axis. For these reasons, a healthy diet composed of healthy nutrients such as probiotics, prebiotics, polyphenols, can prevent many metabolic and inflammatory diseases such as neurodegenerative diseases and obesity. The special Adiponectin role should be taken into account also, in order to be able to use this component as a therapeutic molecule.
Identifiants
pubmed: 33291597
pii: ijms21239255
doi: 10.3390/ijms21239255
pmc: PMC7729837
pii:
doi:
Substances chimiques
Adiponectin
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Curr Opin Biotechnol. 2015 Apr;32:35-41
pubmed: 25448230
Metabolism. 2012 Dec;61(12):1803-8
pubmed: 22789446
Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15;304(2):G211-20
pubmed: 23139216
Sci Rep. 2017 Oct 19;7(1):13537
pubmed: 29051531
Front Immunol. 2019 Nov 27;10:2812
pubmed: 31827477
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16050-5
pubmed: 21876150
Adv Exp Med Biol. 2014;817:357-71
pubmed: 24997042
Cell Host Microbe. 2008 Oct 16;4(4):337-49
pubmed: 18854238
Gastroenterology. 2012 Apr;142(4):844-854.e4
pubmed: 22226658
Immunity. 2009 Oct 16;31(4):677-89
pubmed: 19833089
Nat Med. 2007 Mar;13(3):332-9
pubmed: 17268472
PLoS One. 2015 Oct 01;10(10):e0139721
pubmed: 26426902
BMJ Case Rep. 2017 Mar 21;2017:
pubmed: 28325724
Front Physiol. 2020 Jul 02;11:694
pubmed: 32714204
Neurol Sci. 2020 May;41(5):1125-1131
pubmed: 31897945
Front Immunol. 2017 Nov 02;8:1452
pubmed: 29163522
Sci Transl Med. 2014 Nov 19;6(263):263ra158
pubmed: 25411471
Int J Mol Sci. 2020 Jan 25;21(3):
pubmed: 31991770
Curr Opin Investig Drugs. 2002 Apr;3(4):565-8
pubmed: 12090725
Dig Dis Sci. 2015 Jan;60(1):186-94
pubmed: 25092036
Parkinsonism Relat Disord. 2016 Nov;32:66-72
pubmed: 27591074
Neurochem Res. 2016 Nov;41(11):2819-2835
pubmed: 27553784
Nat Rev Gastroenterol Hepatol. 2013 Aug;10(8):473-86
pubmed: 23797870
PLoS One. 2016 Apr 07;11(4):e0153134
pubmed: 27054321
Neurochem Int. 2018 Nov;120:149-163
pubmed: 30114473
Food Res Int. 2017 Jul;97:364-371
pubmed: 28578061
Immunity. 2009 Sep 18;31(3):368-76
pubmed: 19766080
Eur Rev Med Pharmacol Sci. 2012 Nov;16(13):1765-73
pubmed: 23208960
Gut. 2018 Nov;67(11):1974-1983
pubmed: 28951525
Front Endocrinol (Lausanne). 2019 Jan 30;10:29
pubmed: 30761090
Neural Plast. 2018 Jul 29;2018:4593530
pubmed: 30150999
Front Cell Neurosci. 2014 Dec 22;8:430
pubmed: 25565964
Cell Metab. 2015 Aug 4;22(2):279-90
pubmed: 26166748
Neuroreport. 2004 Aug 26;15(12):1847-50
pubmed: 15305122
Compr Physiol. 2018 Jun 18;8(3):1031-1063
pubmed: 29978896
BMJ. 2009 Feb 05;338:b158
pubmed: 19196745
Obesity (Silver Spring). 2018 May;26(5):792-800
pubmed: 29687645
Genes Brain Behav. 2014 Jan;13(1):69-86
pubmed: 24286462
Rev Neurosci. 2015;26(3):359-70
pubmed: 25741943
Int J Mol Sci. 2017 Mar 09;18(3):
pubmed: 28282917
J Alzheimers Dis. 2013;35(1):179-98
pubmed: 23388174
Immune Netw. 2014 Dec;14(6):277-88
pubmed: 25550694
Am J Physiol Gastrointest Liver Physiol. 2012 Dec 1;303(11):G1288-95
pubmed: 23064760
Int J Mol Sci. 2020 Aug 19;21(17):
pubmed: 32825115
Am J Neurodegener Dis. 2013 Jun 21;2(2):89-107
pubmed: 23844334
Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E506-15
pubmed: 20570822
Eur J Pharmacol. 2015 Oct 15;765:495-502
pubmed: 26386288
J Biol Chem. 2003 Mar 14;278(11):9073-85
pubmed: 12496257
Eur J Neurol. 2019 Feb;26(2):348-355
pubmed: 30300462
Gastroenterology. 2010 Dec;139(6):2102-2112.e1
pubmed: 20600016
Alzheimers Dement. 2017 Jan;13(1):1-7
pubmed: 27583652
Behav Brain Res. 2016 Feb 1;298(Pt B):202-9
pubmed: 26522841
Nat Med. 2003 Jul;9(7):900-6
pubmed: 12808449
J Intern Med. 2014 Apr;275(4):428-36
pubmed: 24410954
Curr Med Chem. 2020;27(26):4372-4391
pubmed: 29521212
Proteomics. 2005 Feb;5(3):687-98
pubmed: 15714464
Immunity. 2016 Apr 19;44(4):951-3
pubmed: 27096322
Gut. 2016 Nov;65(11):1812-1821
pubmed: 26416813
Biomed Res Int. 2015;2015:716920
pubmed: 26290874
Proc Natl Acad Sci U S A. 2016 May 17;113(20):5754-9
pubmed: 27140617
Curr Pharm Biotechnol. 2012 Jan;13(1):191-9
pubmed: 21466438
Br J Nutr. 2010 Aug;104 Suppl 2:S1-63
pubmed: 20920376
PLoS One. 2012;7(3):e33796
pubmed: 22442723
Int J Mol Sci. 2017 Jun 21;18(6):
pubmed: 28635626
Gastroenterology. 2009 Nov;137(5):1716-24.e1-2
pubmed: 19706296
J Alzheimers Dis. 2009;16(2):341-50
pubmed: 19221424
Inflammation. 2012 Dec;35(6):1880-8
pubmed: 22821406
mBio. 2017 Jan 24;8(1):
pubmed: 28119466
Nutrients. 2014 Dec 22;6(12):6020-47
pubmed: 25533011
Clin Psychopharmacol Neurosci. 2015 Dec 31;13(3):239-44
pubmed: 26598580
Toxicol Lett. 2019 Sep 15;312:72-97
pubmed: 31034867
Nutrients. 2013 Sep 26;5(10):3779-827
pubmed: 24077237
Eur J Nutr. 2000 Aug;39(4):164-71
pubmed: 11079736
Alzheimers Res Ther. 2016 Jun 30;8:25
pubmed: 27358067
Expert Opin Investig Drugs. 2008 Feb;17(2):169-84
pubmed: 18230051
Curr Pharm Des. 2019;25(22):2428-2442
pubmed: 31333085
Sci Rep. 2017 Oct 18;7(1):13510
pubmed: 29044140
Int J Food Sci Nutr. 2020 Jun;71(4):509-515
pubmed: 31638838
Mov Disord. 2015 Sep;30(10):1351-60
pubmed: 26179554
Cold Spring Harb Perspect Biol. 2015 Jan 05;7(1):a020412
pubmed: 25561720
Nature. 2016 Jul 06;535(7610):85-93
pubmed: 27383983
PLoS One. 2017 Nov 1;12(11):e0187307
pubmed: 29091972
Nat Rev Immunol. 2018 Apr;18(4):279-287
pubmed: 29109542
Cell Death Dis. 2015 Aug 06;6:e1844
pubmed: 26247729
Ann Neurol. 2011 Jan;69(1):181-92
pubmed: 21280088
Front Neurosci. 2019 Jul 24;13:728
pubmed: 31396030
Front Immunol. 2014 Jul 04;5:311
pubmed: 25071772
Int J Neuropsychopharmacol. 2016 Aug 12;19(8):
pubmed: 26912607
J Biol Chem. 2003 Oct 10;278(41):40352-63
pubmed: 12878598
Curr Drug Targets Immune Endocr Metabol Disord. 2003 Dec;3(4):243-54
pubmed: 14683455
Gastroenterology. 2009 Jul;137(1):262-73
pubmed: 19248781
Neurotox Res. 2020 Feb;37(2):250-263
pubmed: 31811589
Gut. 2018 Sep;67(9):1716-1725
pubmed: 29934437
Inflammopharmacology. 2017 Aug;25(4):415-429
pubmed: 28516374
Front Physiol. 2018 Jul 24;9:982
pubmed: 30140232
Neurobiol Aging. 2007 Jun;28(6):845-55
pubmed: 16714069
Biochem Biophys Res Commun. 2004 Oct 15;323(2):630-5
pubmed: 15369797
Microb Ecol Health Dis. 2015 Feb 02;26:26050
pubmed: 25651996
Adv Exp Med Biol. 2014;817:373-403
pubmed: 24997043
Sci Rep. 2017 Sep 5;7(1):10411
pubmed: 28874832
Clin Endocrinol (Oxf). 2005 Sep;63(3):253-8
pubmed: 16117810
Cell Metab. 2017 Jul 5;26(1):110-130
pubmed: 28625867
Pathol Biol (Paris). 2015 Feb;63(1):35-42
pubmed: 25468489
J Biol Chem. 2002 Aug 16;277(33):29359-62
pubmed: 12087086
Mol Autism. 2016 Nov 29;7:49
pubmed: 27957319
Neurology. 2014 Oct 14;83(16):1410-6
pubmed: 25230996
Cell. 2015 Apr 9;161(2):264-76
pubmed: 25860609
Neurochem Int. 2016 Oct;99:110-132
pubmed: 27346602
Nat Rev Gastroenterol Hepatol. 2018 Nov;15(11):671-682
pubmed: 29844585
Nutrients. 2015 Jul 01;7(7):5309-26
pubmed: 26140539
J Mol Cell Biol. 2016 Apr;8(2):120-8
pubmed: 26993045
Gastroenterology. 2007 Jan;132(1):397-414
pubmed: 17241888
Sci Transl Med. 2019 Jun 12;11(496):
pubmed: 31189717
Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):491-502
pubmed: 28611480
Science. 2007 Jul 13;317(5835):256-60
pubmed: 17569825
J Med Food. 2011 Nov;14(11):1321-9
pubmed: 21663484
Pharmacol Res. 2018 Mar;129:216-226
pubmed: 29170097
Ann Clin Transl Neurol. 2017 Jul 11;4(8):591-600
pubmed: 28812049
J Am Geriatr Soc. 2009 Jan;57(1):11-7
pubmed: 19054188
Mov Disord. 2015 Mar;30(3):350-8
pubmed: 25476529
Neuropsychopharmacology. 2012 May;37(6):1444-54
pubmed: 22353759
Sci Transl Med. 2009 Nov 11;1(6):6ra14
pubmed: 20368178
J Diabetes Complications. 2017 Feb;31(2):295-303
pubmed: 27771154
PLoS One. 2017 Dec 21;12(12):e0186205
pubmed: 29267309
Front Physiol. 2015 Nov 03;6:304
pubmed: 26578976
BMC Infect Dis. 2014 Feb 12;14:79
pubmed: 24520976
Curr Opin Pharmacol. 2020 Jun;52:9-17
pubmed: 32388413
Nat Med. 2013 Dec;19(12):1584-96
pubmed: 24309662
Nat Metab. 2019 Jan;1(1):34-46
pubmed: 32694818
Carbohydr Res. 2016 Sep 2;432:62-70
pubmed: 27448325
J Neurogastroenterol Motil. 2018 Jan 30;24(1):30-42
pubmed: 29291606
Medicina (Kaunas). 2020 Aug 27;56(9):
pubmed: 32867260
Adv Exp Med Biol. 2014;817:115-33
pubmed: 24997031
J Clin Gastroenterol. 2008 Sep;42 Suppl 3 Pt 2:S218-23
pubmed: 18685503
Genes Nutr. 2020 Jun 26;15(1):12
pubmed: 32586265
FASEB J. 2008 Jul;22(7):2416-26
pubmed: 18326786
Front Immunol. 2017 Jul 31;8:895
pubmed: 28824624
Aliment Pharmacol Ther. 2015 Jul;42(2):158-79
pubmed: 26011307
J Neurosci. 2009 Apr 15;29(15):4820-8
pubmed: 19369550
Int J Mol Sci. 2020 Mar 16;21(6):
pubmed: 32188008
Microbiome. 2019 Jun 29;7(1):98
pubmed: 31255176
Therap Adv Gastroenterol. 2009 Jul;2(4):37-44
pubmed: 21180553
Kaohsiung J Med Sci. 2018 Mar;34(3):134-141
pubmed: 29475460
Front Microbiol. 2016 Nov 30;7:1934
pubmed: 27965654
Free Radic Biol Med. 2016 Apr;93:155-64
pubmed: 26849947
Biochem Biophys Res Commun. 2004 Apr 9;316(3):924-9
pubmed: 15033490
Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3047-52
pubmed: 21282636
Maturitas. 2018 Oct;116:43-53
pubmed: 30244778
Expert Rev Mol Med. 2011 Sep 20;13:e30
pubmed: 21933454
Nutrients. 2011 Oct;3(10):858-76
pubmed: 22254083
J Crohns Colitis. 2015 Jul;9(7):532-40
pubmed: 25895879
J Alzheimers Dis. 2016;51(4):979-84
pubmed: 26967229